X-Ray Crystallography of Biomacromolecules: A Practical Guide

X-Ray Crystallography of Biomacromolecules: A Practical Guide

Author(s): Dr. Albrecht Messerschmidt

Published Online: 5 JAN 2007

Print ISBN: 9783527313969

Online ISBN: 9783527610129

DOI: 10.1002/9783527610129

About this Book

Written by one of the most significant contributors to the progress of protein crystallography, this practical guide contains case studies, a troubleshooting section and pointers on data interpretation. It covers the theory, practice and latest achievements in x-ray crystallography, such that any researcher in structural biology will benefit from this extremely clearly written book.
Part A covers the theoretical basis and such experimental techniques as principles of x-ray diffraction, solutions for the phase problem and time-resolved x-ray crystallography. Part B includes case studies for different kinds of x-ray crystal structure determination, such as the MIRAS and MAD techniques, molecular replacement, and the difference Fourier technique.

Table of contents

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  1. Part I: Principles and Methods

  2. Part II: Practical Examples

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