Novel Therapeutic Proteins: Selected Case Studies

Novel Therapeutic Proteins: Selected Case Studies

Editor(s): Klaus Dembowsky, Peter Stadler

Published Online: 18 DEC 2007

Print ISBN: 9783527302703

Online ISBN: 9783527613021

DOI: 10.1002/9783527613021

About this Book

This book describes medical applications of recombinant proteins and monoclonal antibodies, some of which have already been on the market for several years while others have only recently been launched. It also highlights the manufacturing processes for individual products, the strategies that were taken by companies in the clinical development, and the hurdles that were encountered in clinical trials and had to be overcome before approval by regulatory authorities. Finally, this book illustrates strategies to modify and improve the pharmacodynamic and pharmacokinetic properties of naturally occurring proteins thus paving the way for a new era in biotechnology.
Foreword written by Jürgen Drews.

Table of contents

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  1. Part 1: Introduction and Overview

  2. Part 2: Recombinant Hormones

    1. Chapter 3

      Human Recombinant Growth Hormone (pages 58–85)

      Carmen Ariznavarreta Ruiz and Jesús A. F. Tresguerres

  3. Part 3: Recombinant Cytokines and their Receptors

    1. Chapter 6

      Interferon β-1b in Multiple Sclerosis (pages 129–145)

      Bernd Aufdembrinke, Reinhard Horowski and Joachim-Friedrich Kapp

  4. Part 4: Recombinant Enzymes. Enzyme Activators. and Inhibitors

  5. Part 5: Recombinant Vaccines

  6. Part 6: Monoclonal Antibodies

    1. You have free access to this content
    1. You have free access to this content