Bacterial Toxins: Tools in Cell Biology and Pharmacology

Bacterial Toxins: Tools in Cell Biology and Pharmacology

Editor(s): Klaus Aktories

Published Online: 5 JUN 2008

Print ISBN: 9783527308811

Online ISBN: 9783527614615

DOI: 10.1002/9783527614615

About this Book

This is a survey of well characterized and recently discovered bacterial protein toxins. Leading investigators of the respective toxins review the various molecular mechanisms of action, ranging from toxin-induced ADP-ribosylation up to membrane perforation by pore-forming toxins. Thy also describe the consequences on host physiology before focusing on potential applications as cell biological and pharmacological tools for research and medical applications. Detailed descriptions of the methodology include the engineering and use of modified and chimeric toxins for better performance.
A solid introduction to toxin structure and functions, as well as a valuable source of methodology for researchers in molecular biology, pharmacology and experimental medicine.

Table of contents

    1. You have free access to this content
    2. Chapter 17

      Pore-Forming Toxins (pages 241–257)

      S. Bhakdi, A. Valeva, I. Walev, U. Weller and M. Palmer

    3. Chapter 19

      Toxins as Transporting Tools (pages 273–294)

      S. Olsnes, O. Klingenberg, R. Muñoz, P. Ø. Falnes and A. Wiedlocha

    4. You have free access to this content

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