Carbohydrates in Chemistry and Biology

Carbohydrates in Chemistry and Biology

Author(s): Prof. Dr. Beat Ernst, Prof. Dr. Gerald W. Hart, Prof. Dr. Pierre Sinaý

Published Online: 24 APR 2008

Print ISBN: 9783527295111

Online ISBN: 9783527618255

DOI: 10.1002/9783527618255

About this Book

Carbohydrate Chemistry and Glycobiology have witnessed a rapid expansion during the last few years with the development of numerous new, imaginative and efficient syntheses which provide further insight into structures and biological interactions of glycoconjugates. Glycosylation reactions are widely used in the synthesis of pharmaceuticals and bio-active compounds. In biology and medicine oligosaccharides play a central role in immuno-stimulation, cancer or allergic responses. Glycoscience is a very instructive example of how one common topic of interest stimulates both chemistry and biology to collectively open scientific frontiers.
This synergy is made visible in this work. Three leading experts in the fields of Glycochemistry and Glycobiology have invited numerous renowned authors to provide a comprehensive overview of the recent advances and findings in Glycoscience. This four-volume handbook presents an integrated and cutting-edge view, and covers all chemical aspects, such as syntheses and analysis of carbohydrates and oligosaccharides, as well as the biological role and activity of oligosaccharides and carbohydrate/protein interactions.

Table of contents

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  1. Part I.1: Chemistry of Saccharides: Chemical Synthesis of Glycosides and Glycomimetics - I Chemical Synthesis of Glycosides

    1. Chapter 6

      Glycosylation Methods: Use of n-Pentenyl Glycosides (pages 135–154)

      Bert Fraser-Reid, G. Anilkumar, Mark R. Gilbert, Subodh Joshi and Ralf Kraehmer

    2. Chapter 7

      Glycosylidene Diazirines (pages 155–175)

      Andrea Vasella, Bruno Bernet, Martin Weber and Wolfgang Wenger

  2. Part I.1: Chemistry of Saccharides: Chemical Synthesis of Glycosides and Glycomimetics - II Synthesis of Oligosaccharide Mimics

    1. Chapter 20

      Synthesis of C-Oligosaccharides (pages 495–530)

      Troels Skrydstrup, Boris Vauzeilles and Jean-Marie Beau

  3. Part I.2: Chemistry of Saccharides: Enzymatic Synthesis of Glycosides and Carbohydrate-Receptor Interaction - III Enzymatic Synthesis of Glycosides

  4. Part I.2: Chemistry of Saccharides: Enzymatic Synthesis of Glycosides and Carbohydrate-Receptor Interaction - IV Carbohydrate-Protein Interactions

    1. Chapter 32

      Structural Analysis of Oligosaccharides: FAB-MS, ES-MS and MALDI-MS (pages 915–945)

      Anne Dell, Howard R. Morris, Richard Easton, Stuart Haslam, Maria Panico, Mark Sutton-Smith, Andrew J. Reason and Kay-Hooi Khoo

  5. Part I.2: Chemistry of Saccharides: Enzymatic Synthesis of Glycosides and Carbohydrate-Receptor Interaction - V Carbohydrate-Protein Interactions

  6. Part I.2: Chemistry of Saccharides: Enzymatic Synthesis of Glycosides and Carbohydrate-Receptor Interaction - VI Carbohydrate-Nucleic Acid Interactions

  7. Part II.3: Biology of Saccharides: Biosynthesis and Degradation of Glycoconjugates - I Biosynthesis of Glycoconjugates

    1. Chapter 49

      The Galactosyltransferases (pages 175–196)

      Nancy L. Shaper, Martin Charron, Neng-Wen Lo, Jane R. Scocca and Joel H. Shaper

    2. Chapter 53

      Carbohydrate Sulfotransferases (pages 245–260)

      Steven D. Rosen, Annette Bistrup and Stefan Hemmerich

    3. Chapter 64

      The Biosynthesis of GPI Anchors (pages 417–433)

      Yasu S. Morita, Alvaro Acosta-Serrano and Paul T. Englund

  8. Part II.3: Biology of Saccharides: Biosynthesis and Degradation of Glycoconjugates - II Glycosidases

    1. Chapter 68

      Sialidases (pages 485–495)

      Garry Taylor, Susan Crennell, Carl Thompson and Marina Chuenkova

  9. Part II.4: Biology of Saccharides: Lectins and Saccharides Biology - III Lectins

    1. Chapter 77

      Galectins (pages 625–647)

      Douglas N. W. Cooper and Samuel H. Barondes

  10. Part II.4: Biology of Saccharides: Lectins and Saccharides Biology - IV Saccharide Biology

    1. Chapter 87

      The Primary Cell Walls of Higher Plants (pages 783–808)

      Jocelyn K. C. Rose, Malcolm A. O'Neill, Peter Albersheim and Alan Darvill

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