Protein Degradation Series: 4 Volume Set

Protein Degradation Series: 4 Volume Set

Editor(s): R. John Mayer, Aaron J. Ciechanover, Martin Rechsteiner

Published Online: 14 DEC 2007

Print ISBN: 9783527318780

Online ISBN: 9783527619320

DOI: 10.1002/9783527619320

About this Book

This series of four topical volumes includes more than 50 contributions covering all aspects of the molecular biology and physiology of controlled protein breakdown in higher organisms via the ubiquitin-proteasome pathway. The editors and authors comprise virtually all the top scientists in the field, including the pioneers of protein degradation research and the 2004 Nobel laureate in chemistry.
Each volume highlights a different aspect of the field, namely ubiquitin and the chemistry of life, as well as the cell biology and pathology of the ubiquitin-proteasome system, with the individual volumes featuring their own separate indices. Together, all four volumes provide the most comprehensive reference on protein degradation available.

Table of contents

  1. Part I: Ubiquitin and the Chemistry of Life

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    2. Chapter 10

      Molecular Machines for Protein Degradation (pages 248–287)

      Matthias Bochtler, Michael Groll, Hans Brandstetter, Tim Clausen and Robert Huber

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  2. Part II: The Ubiquitin–Proteasome System

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  3. Part III: Cell Biology of the Ubiquitin–Proteasome System

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    2. Chapter 7

      p97 and Ubiquitin: A Complex Story (pages 149–193)

      Louise C. Briggs, Ingrid Dreveny, Valerie E. Pye, Fabienne Beuron, Ciarán F. McKeown, Xiaodong Zhang and Paul S. Freemont

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  4. Part IV: The Ubiquitin–Proteasome System and Disease

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    2. Chapter 10

      Parkin and Neurodegeneration (pages 211–236)

      Sathya R. Sriram, Valina L. Dawson and Ted M. Dawson

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