Handbook of Dendritic Cells: Biology, Diseases, and Therapies

Copyright © 2006 WILEY-VCH Verlag GmbH & Co. KGaA

Handbook of Dendritic Cells: Biology, Diseases, and Therapies

Editor(s): Manfred B. Lutz, Nikolaus Romani, Alexander Steinkasserer

Published Online: 26 MAR 2008

Print ISBN: 9783527311095

Online ISBN: 9783527619696

DOI: 10.1002/9783527619696

About this Book

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This is the most comprehensive handbook on dendritic cells, featuring an introduction by Ralph M. Steinman and written by top experts. In three volumes, it covers all aspects from molecular cell biology to clinical applications, highlighting the role of dendritic cells in fighting cancer, virus infections, and autoimmune diseases.
The first section on cell biology looks at dendritic cell development, circulating cells, T cell priming, Th1 and Th2 decision and CTL priming. A second part on dendritic cells in disease deals with parasites, bacteria, viruses, autoimmunity, allergies, asthma and cancer. The final section on therapeutic applications includes viral infections and antigen delivery.

Table of contents

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      Frontmatter (pages I–37)

  2. Part A: Dendritic Cell Biology

    1. Chapter 1

      Introduction to Some of the Issues and Mysteries Considered in this Book on Dendritic Cells (pages 3–11)

      Ralph M. Steinman

  3. Part A: Dendritic Cell Biology - I Dendritic Cell Development

    1. Chapter 2

      Bone Marrow Progenitors of Dendritic and Natural Interferon-producing Cells (pages 13–25)

      Markus G. Manz

    2. Chapter 3

      Growth Factors (pages 27–51)

      Herbert Strobl, Barbara Platzer, Almut Jörgl, Sabine Taschner, Leonhard Heinz and Peter Reisner

    3. Chapter 4

      Transcription Factors: Deciphering the Transcription Factor Network of Dendritic Cell Development (pages 53–71)

      Thomas Hieronymus and Martin Zenke

  4. Part A: Dendritic Cell Biology - II Sentinel Dendritic Cells in Nonlymphoid Organs

    1. Chapter 5

      Epidermal Langerhans Cells (pages 73–100)

      Nikolaus Romani, Christoph H. Tripp, Gudrun Ratzinger, Christine Heufler, Franz Koch, Sem Saeland and Patrizia Stoitzner

    2. Chapter 6

      Characterization of Dendritic Cells and other Antigen-presenting Cells in the Eye (pages 101–118)

      Joan Stein-Streilein

    3. Chapter 7

      Toll-like Receptors (pages 119–127)

      Hubertus Hochrein and Hermann Wagner

    4. Chapter 8

      C-type Lectins on Dendritic Cells: Antigen Receptors and Modulators of Immune Responses (pages 129–140)

      Yvette Van Kooyk and Teunis B. H. Geijtenbeek

    5. Chapter 9

      Scavenger Receptors on Dendritic Cells (pages 141–163)

      Emma J. McKenzie, Subhankar Mukhopadhyay, Siamon Gordon and Luisa Martinez-Pomares

    6. Chapter 10

      Production of the Long Pentraxin PTX3 by Myeloid Dendritic Cells: Linking Cellular and Humoral Innate Immunity (pages 165–174)

      Paola Allavena, Barbara Bottazzi, Andrea Doni, Luigina Romani, Cecilia Garlanda and Alberto Mantovani

    7. Chapter 11

      Gene Profiling of Dendritic cells during Host–Pathogen Interactions (pages 175–197)

      Maria Foti, Francesca Granucci, Mattia Pelizzola, Norman Pavelka, Ottavio Beretta, Caterina Vizzardelli, Matteo Urbano, Ivan Zanoni, Giusy Capuano, Francesca Mingozzi, François Trottein, Toni Aebischer and Paola Ricciardi-Castagnoli

  5. Part A: Dendritic Cell Biology - III Dendritic Cells in Secondary Lymphoid Organs

    1. Chapter 12

      Dendritic Cell Subtypes (pages 199–217)

      Ken Shortman and Jóse A. Villadangos

  6. Part A: Dendritic Cell Biology - IV Circulating Dendritic Cells and their Precursors

    1. Chapter 13

      pDC: From Plasmacytoid Dendritic Cell Precursors to Professional Type 1 Interferon-producing Cells (pages 219–251)

      Yong-Jun Liu, Holger Kanzler, Yui-Hsi Wang, Yi-Hong Wang, Michel Gilliet, Wei Cao and Tomoki Ito

    2. Chapter 14

      Monocyte subsets and their relation to DCs (pages 253–278)

      Brigitte Senechal, Darin Fogg, Gaelle Elain and Frederic Geissmann

  7. Part A: Dendritic Cell Biology - V Dendritic Cell Migration

    1. Chapter 15

      Steady State Migration of Dendritic Cells in Lymph (pages 279–293)

      Gordon Macpherson, Simon Milling, Emma Turnbull and Ulf Yrlid

    2. Chapter 16

      Multiple Pathways to Control DC Migration (pages 295–312)

      Karel Otero, Elena Riboldi, Annalisa Del Prete, Annunciata Vecchi, Fabio Facchetti, Alberto Mantovani and Silvano Sozzani

  8. Part A: Dendritic Cell Biology - VI T-cell Activation and Co-stimulation

    1. Chapter 17

      Antigen Processing and Presentation: CD1d and NKT cells (pages 313–341)

      Serani L. H. Van Dommelen, Dale I. Godfrey and Mark J. Smyth

    2. Chapter 18

      The Role of Dendritic Cells in T-cell Activation and Differentiation (pages 343–354)

      Federica Sallusto and Antonio Lanzavecchia

    3. Chapter 19

      Cytokines Produced by Dendritic Cells (pages 355–383)

      David F. Tough

  9. Part A: Dendritic Cell Biology - VII Th1 and Th2 Decision

    1. Chapter 20

      The Plasticity of Dendritic Cells Populations in Promoting Th-cell Responses (pages 385–403)

      André Boonstra, Giorgio Trinchieri and Anne O'Garra

    2. Chapter 21

      Microbial Instruction of Dendritic Cells (pages 405–426)

      Esther C. De Jong, Hermelijn H. Smits, Eddy A. Wierenga and Martien L. Kapsenberg

  10. Part A: Dendritic Cell Biology - VIII CTL Priming and Crosspresentation

    1. Chapter 22

      Crossprocessing and Crosspresentation (pages 427–453)

      Mojca Škoberne and Nina Bhardwaj

    2. Chapter 23

      A Systems Biologist's View of Dendritic Cell–Cytotoxic T Lymphocyte Interaction (pages 455–479)

      Burkhard Ludewig and Gennady Bocharov

  11. Part A: Dendritic Cell Biology - IX Dendritic Cells Cross-talk with Other Cell Types

    1. Chapter 24

      Dendritic Cells and Natural Killer Cells (pages 481–497)

      Magali Terme and Laurence Zitvogel

    2. Chapter 25

      Intercellular Communication via Protein Transfer (pages 499–515)

      Marca H. M. Wauben

  12. Part A: Dendritic Cell Biology - X Tolerogenic Dendritic Cells

    1. Chapter 26

      Differentiation Stages and Subsets of Tolerogenic Dendritic Cells (pages 517–543)

      Manfred B. Lutz

    2. Chapter 27

      Dendritic Cell Manipulation with Biological and Pharmacological Agents to Induce Regulatory T Cells (pages 545–567)

      Luciano Adorini and Giuseppe Penna

    3. Chapter 28

      Surface Molecules Involved in the Induction of Tolerance by Dendritic Cells (pages 569–589)

      Laura C. Bonifaz

    4. Chapter 29

      Interaction Between Dendritic Cells and Apoptotic Cells (pages 591–618)

      Adriana T. Larregina and Adrian E. Morelli

    5. Chapter 30

      Pharmacologically Modified Dendritic Cells: A Route to Tolerance-associated Genes (pages 619–647)

      Kathleen F. Nolan, Stephen F. Yates, Alison M. Paterson, Paul J. Fairchild and Herman Waldmann

  13. Part B: Dendritic Cells in Disease - XI Parasites

    1. Chapter 31

      Malaria (pages 651–668)

      Britta C. Urban and Francis M. Ndungu

    2. Chapter 32

      Dendritic Cells in Leishmaniasis: Regulators of Immunity and Tools for New Immune Intervention Strategies (pages 669–691)

      Heidrun Moll

    3. Chapter 33

      Sentinel and Regulatory Functions of Dendritic Cells in the Immune Response to Toxoplasma gondii (pages 693–707)

      Alan Sher, Felix Yarovinsky, Romina Goldszmid, Julio Aliberti and Dragana Jankovic

    4. Chapter 34

      Schistosoma (pages 709–722)

      Andrew S. Macdonald and Edward J. Pearce

  14. Part B: Dendritic Cells in Disease - XII Bacteria

    1. Chapter 35

      Dendritic Cells and Immunity to Salmonella (pages 723–744)

      Mary Jo Wick

    2. Chapter 36

      Dendritic Cells in Tuberculosis (pages 745–758)

      Ulrich E. Schaible and Florian Winau

    3. Chapter 37

      Dendritic Cell–Epithelial Cell Interactions in Response to Intestinal Bacteria (pages 759–771)

      Maria Rescigno

  15. Part B: Dendritic Cells in Disease - XIII Viruses

    1. Chapter 38

      Sleeping with the Enemy: The Insidious Relationship between Dendritic Cells and Immunodeficiency Viruses (pages 773–811)

      L. Vachot, S. G. Turville, S. Trapp, S. Peretti, G. Morrow, I. Frank and M. Pope

    2. Chapter 39

      Cytomegalovirus Infection of Dendritic Cells (pages 813–828)

      Brigitte Sénéchal and James W. Young

    3. Chapter 40

      Interactions of Hemorrhagic Fever Viruses with Dendritic Cells (pages 829–854)

      Stefan Pöhlmann

    4. Chapter 41

      Dendritic Cells in Measles Virus Pathogenesis (pages 855–874)

      Marion Abt, Nora Mueller and Sibylle Schneider-Schaulies

    5. Chapter 42

      Dendritic Cells and Herpes Simplex Virus Type 1 (pages 875–896)

      Alexander T. Prechtel and Alexander Steinkasserer

    6. Chapter 43

      Epstein–Barr Virus (pages 897–914)

      Christian Münz

  16. Part B: Dendritic Cells in Disease - XIV Fungi

    1. Chapter 44

      Dendritic Cells in Immunity and Vaccination against Fungi (pages 915–934)

      Luigina Romani and Paolo Puccetti

  17. Part B: Dendritic Cells in Disease - XV Autoimmunity

    1. Chapter 45

      Dendritic Cells in Autoimmune Diseases (pages 935–966)

      Alexis Mathian, Sophie Koutouzov, Virginia Pascual, A. Karolina Palucka and Jacques Banchereau

  18. Part B: Dendritic Cells in Disease - XVI Transplantation

    1. Chapter 46

      Role of Dendritic Cells in Graft Rejection and Graft-versus-host Disease (pages 967–982)

      Véronique Flamand and Michel Goldman

    2. Chapter 47

      Dendritic Cells and Transplantation Tolerance (pages 983–1016)

      Paul J. Fairchild, Stephen F. Yates and Herman Waldmann

    3. Chapter 48

      Dendritic Cells, Immune Regulation and Transplant Tolerance (pages 1017–1045)

      Giorgio Raimondi and Angus W. Thomson

  19. Part B: Dendritic Cells in Disease - XVII Allergy, Asthma

    1. Chapter 49

      Nickel Presentation to T Cells in Contact Hypersensitivity (pages 1047–1058)

      H. U. Weltzien, K. Gamerdinger and H.-J. Thierse

    2. Chapter 50

      Dendritic Cells in Asthma (pages 1059–1079)

      Hamida Hammad and Bart N. Lambrecht

  20. Part B: Dendritic Cells in Disease - XVIII Cancer

    1. Chapter 51

      Dendritic Cells in Human Cancer (pages 1081–1092)

      Casey A. Carlos and Olivera J. Finn

  21. Part C: Therapeutical Applications of Dendritic Cells - XIX Cancer

    1. Chapter 52

      Dendritic Cell Subsets as Targets and Vectors for Vaccination (pages 1094–1115)

      Hideki Ueno, Joseph Fay, Jacques Banchereau and A. Karolina Palucka

    2. Chapter 53

      Renal Cell Carcinoma (pages 1117–1127)

      Martin Thurnher, Thomas Putz, Andrea Rahm, Hubert Gander, Reinhold Ramoner, Georg Bartsch, Lorenz Höltl and Claudia Falkensammer

  22. Part C: Therapeutical Applications of Dendritic Cells - XX Antigen Delivery

    1. Chapter 54

      Crosspresentation and Loading of Tumor Antigens for Dendritic Cell Vaccination against Cancer (pages 1129–1142)

      Madhav V. Dhodapkar

    2. Chapter 55

      Nucleic Acid Transfer (pages 1143–1171)

      Niels Schaft, Jan Dörrie and Dirk M. Nettelbeck

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      Color Plates (pages LIII–LXXIII)

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      Color Plates (pages LIII–LXVII)

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      Color Plates (pages LIII–LXVI)

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      Subject Index (pages 1173–1226)

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