Handbook of Genome Research: Genomics, Proteomics, Metabolomics, Bioinformatics, Ethical and Legal Issues

Handbook of Genome Research: Genomics, Proteomics, Metabolomics, Bioinformatics, Ethical and Legal Issues

Editor(s): Christoph W. Sensen

Published Online: 29 JAN 2008

Print ISBN: 9783527313488

Online ISBN: 9783527619733

DOI: 10.1002/9783527619733

About this Book

In this unique presentation of a revolutionary field of science, the first section introduces the domains of application for genomics and bioinformatics, such as sequencing and the comparative sequence analysis of model organisms, investigating genetically influenced diseases, the development of new active substances, agri-food and environmental genomics.
There then follows an overview of current topics central to DNA technologies, proteomics, metabolomics and bioinformatics, including such hot topics as DNA chip fabrication, yeast two hybrid analysis, tools for gene expression studies, metabolic networks and systems biology.
The whole is rounded off by four chapters on the ethical, legal and social aspects of this sensitive topic.

Table of contents

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  1. Part I: Key Organisms

    1. Chapter 1

      Genome Projects on Model Organisms (pages 2–43)

      Alfred Pühler, Doris Jording, Jürn Kalinowski, Detlev Buttgereit, Renate Renkawitz-Pohl, Lothar Altschmied, Antoin Danchin, Agnieszka Sekowska, Horst Feldmann, Hans-Peter Klenk and Manfred Kröger

  2. Part II: Genomic and Proteomic Technologies

    1. Chapter 6

      DNA Sequencing Technology (pages 129–180)

      Lyle R. Middendorf, Patrick G. Humphrey, Narasimhachari Narayanan and Stephen C. Roemer

    2. Chapter 9

      A DNA Microarray Fabrication Strategy for Research Laboratories (pages 223–238)

      Daniel C. Tessier, Mélanie Arbour, François Benoit, Hervé Hogues and Tracey Rigby

    3. Chapter 11

      Yeast Two-hybrid Technologies (pages 261–272)

      Gregor Jansen, David Y. Thomas and Stephanie Pollock

    4. Chapter 12

      Structural Genomics (pages 273–295)

      Aalim M. Weljie, Hans J. Vogel and Ernst M. Bergmann

  3. Part III: Bioinformatics

    1. Chapter 16

      Genome Data Representation Through Images: The MAGPIE/Bluejay System (pages 383–414)

      Andrei Turinsky, Paul M. K. Gordon, Emily Xu, Julie Stromer and Christoph W. Sensen

  4. Part IV: Ethical, Legal and Social Issues

  5. Part V: Outlook

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