Cell Junctions: Adhesion, Development, and Disease

Copyright © 2008 Wiley-VCH Verlag GmbH & Co. KGaA

Cell Junctions: Adhesion, Development, and Disease

Editor(s): Susan E. LaFlamme, Andrew P. Kowalczyk

Published Online: 11 APR 2008

Print ISBN: 9783527318827

Online ISBN: 9783527622092

DOI: 10.1002/9783527622092

About this Book

Product Information

About The Product

This long-awaited, first comprehensive book on this topic of fundamental importance in our understanding of cancer begins with an overview of cellular junctions, before covering cell-matrix junctions, cell-cell junctions and cell-matrix and cell-cell adhesion in separate sections.
Of high interest to cell and molecular biologists, cancer researchers, oncologists, biochemists, pharmaceutists and those working in the pharmaceutical industry.

Table of contents

    1. You have free access to this content
      Front Matter (pages I–XV)

  2. Part One: Cell–Matrix Junctions

    1. Chapter 1

      The Ins and Outs of Integrin Signaling (pages 1–23)

      Asoka Banno and Mark H. Ginsberg

    2. Chapter 2

      Integrin Signaling Through Focal Adhesion Kinase (pages 25–46)

      Youngdong Yoo and Jun-Lin Guan

    3. Chapter 3

      The Paxillin Family and Tissue Remodeling (pages 47–69)

      David A. Tumbarello and Christopher E. Turner

    4. Chapter 4

      Adhesion Dynamics in Motile Cells (pages 71–88)

      Christa L. Cortesio, Keefe T. Chan and Anna Huttenlocher

    5. Chapter 5

      Integrin Trafficking (pages 89–107)

      Prof. Dr. Susan E. LaFlamme, Feng Shi and Jane Sottile

    6. Chapter 6

      Hemidesmosomes and their Components: Adhesion versus Signaling in Health and Disease (pages 109–133)

      Kristina Kligys, Kevin Hamill and Jonathan C. R. Jones

    7. Chapter 7

      Cell Matrix Adhesion in Three Dimensions (pages 135–149)

      Patricia J. Keely

  3. Part Two: Cell–Cell Junctions

    1. Chapter 8

      Armadillo Repeat Proteins at Epithelial Adherens Junctions (pages 151–167)

      Laura J. Lewis-Tuffin and Panos Z. Anastasiadis

    2. Chapter 9

      Signaling To and Through The Endothelial Adherens Junction (pages 169–195)

      Deana M. Ferreri and Peter A. Vincent

    3. Chapter 10

      Gap Junctions: Connexin Functions and Roles in Human Disease (pages 197–216)

      Michael Koval

    4. Chapter 11

      Tight Junctions in Simple and Stratified Epithelium (pages 217–233)

      Cara J. Gottardi and Carien M. Niessen

    5. Chapter 12

      Desmosomes in Development and Disease (pages 235–249)

      Ansgar Schmidt and Peter J. Koch

    6. Chapter 13

      Cadherin Trafficking and Junction Dynamics (pages 251–270)

      Christine M. Chiasson and Prof. Andrew P. Kowalczyk

  4. Part Three: Cell–Matrix and Cell–Cell Crosstalk

    1. Chapter 14

      Crosstalk Between Cell–Cell and Cell–Matrix Adhesion (pages 271–294)

      C. Michael DiPersio

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      Index (pages 295–301)

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