Detection of Highly Dangerous Pathogens: Microarray Methods for BSL 3 and BSL 4 Agents

Copyright © 2009 Wiley-VCH Verlag GmbH & Co. KGaA

Detection of Highly Dangerous Pathogens: Microarray Methods for BSL 3 and BSL 4 Agents

Editor(s): Tanja Kostic, Patrick Butaye, Jacques Schrenzel

Published Online: 7 OCT 2009

Print ISBN: 9783527322756

Online ISBN: 9783527626687

DOI: 10.1002/9783527626687

About this Book

Product Information

About The Product

Written by leading experts in the field as part of an interdisciplinary pan-European research program funded by the EU, the results provided in this booklet provide a unique and comprehensive overview of how microarray technology can be used in safely tracking the most highly dangerous pathogens. A must-have for public health agencies focused on bioterrorism as well as all laboratories working with BSL3 and/or BSL 4 agents.

Table of contents

    1. You have free access to this content
      Front Matter (pages I–XVIII)

    1. Chapter 1

      Introduction to Microarray-Based Detection Methods (pages 1–34)

      Prof. Jacques Schrenzel, Dr. Tanja Kostic, Levente Bodrossy and Patrice Francois

  3. Part I: Methods

    1. Chapter 2

      Long Oligonucleotide Microarray-Based Microbial Detection (pages 35–46)

      Dr. Tanja Kostic and Levente Bodrossy

    2. Chapter 3

      Sequence-Specific End-Labeling of Oligonucleotides (pages 47–57)

      Dr. Tanja Kostic and Levente Bodrossy

    3. Chapter 4

      Non-Cognate Approaches for Pathogen Detection on Microarrays (pages 59–65)

      Antoine Huyghe, Patrice Francois, Yvan Charbonnier, David Hernandez, Jonathan Hibbs and Prof. Jacques Schrenzel

    4. Chapter 5

      Patterning Techniques for Array Platforms (pages 67–84)

      Erhan Pişkin, Bora Garipcan, Gökhan Demirel and Oğuzhan Çağlayan

    5. Chapter 6

      Probe Immobilization Techniques in Array Technologies (pages 85–104)

      Erhan Pişkin, Bora Garipcan and Memed Duman

  4. Part II: Identification

    1. Chapter 7

      Low-Cost and Low-Density Microarrays – A Novel Technique for Identification and Typing of Microorganisms (pages 105–112)

      Dimitrios Frangoulidis, Volker Heiser, Olfert Landt and Hermann Meyer

    2. Chapter 8

      DNA Microarray Technique for Detection and Identification of Viruses Causing Encephalitis and Hemorrhagic Fever (pages 113–123)

      Henrik Nordström, Kerstin I. Falk, Peter Nilsson and Åke Lundkvist

    3. Chapter 9

      Microarrays for Genomotyping of Pathogens (pages 125–132)

      Jasper Kieboom, Ingrid Voskamp and Martien P. Broekhuijsen

  5. Part III: Typing

    1. Chapter 10

      Single Nucleotide Polymorphisms as Targets for DNA-Based Identification and Typing of Biosafety Level 3 Bacteria (pages 133–145)

      Pierre Wattiau, Pieter Vos and David Fretin

    2. Chapter 11

      Use of a Microchip to Detect Antibiotic Resistance Genes in Bacillus anthracis (pages 147–152)

      Vincent Perreten and Joachim Frey

  6. Part IV: Quality Control

    1. Chapter 12

      Progress towards Development of Microarrays for Routine Diagnostic Use (pages 153–168)

      Karen Kempsell, Sonal Shah, Susanna Sherwin, Richard Vipond and Nigel Silman

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      Index (pages 169–173)

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