Redox Signaling and Regulation in Biology and Medicine

Copyright © 2009 Wiley-VCH Verlag GmbH & Co. KGaA

Redox Signaling and Regulation in Biology and Medicine

Editor(s): Claus Jacob, Paul G. Winyard

Published Online: 28 MAY 2009

Print ISBN: 9783527319251

Online ISBN: 9783527627585

DOI: 10.1002/9783527627585

About this Book

Product Information

About The Product

This first entry-level guide to the multifaceted field takes readers one step further than existing textbooks. In an easily accessible manner, the authors integrate the biochemistry, cell biology and medical implications of intracellular redox processes, demonstrating that complex science can be presented in a clear and almost entertaining way.
Perfect for students and junior researchers, this is an equally valuable addition to courses in biochemistry, molecular biology, cell biology, and human physiology.

Table of contents

    1. You have free access to this content
      Front Matter (pages I–XXXIII)

    2. Chapter 1

      Introduction (pages 1–11)

      Jun. -Prof. Dr. Claus Jacob and Prof. Dr. Paul G. Winyard

    3. Chapter 2

      Biological Systems Relevant for Redox Signaling and Control (pages 13–43)

      Thomas R. Hurd and Michael P. Murphy

    4. Chapter 3

      Cellular Generation of Oxidants: Relation to Oxidative Stress (pages 45–61)

      Lars-Oliver Klotz and Prof Helmut Sies

    5. Chapter 4

      The Chemical Basis of Biological Redox Control (pages 63–122)

      Jun. -Prof. Dr. Claus Jacob, Mandy Doering and Torsten Burkholz

    6. Chapter 5

      Protein Glutathiolation (pages 123–141)

      Pietro Ghezzi and Paolo Di Simplicio

    7. Chapter 6

      Structure and Function of the Human Peroxiredoxin-Based Antioxidant System: the Interplay between Peroxiredoxins, Thioredoxins, Thioredoxin Reductases, Sulfiredoxins and Sestrins (pages 143–179)

      Katalin É. Szabó, Kirsty Line, Paul Eggleton, Jennifer A. Littlechild and Prof. Dr. Paul G. Winyard

    8. Chapter 7

      Hydrogen Peroxide and Cysteine Protein Signaling Pathways (pages 181–195)

      Ewald Schröder and Philip Eaton

    9. Chapter 8

      Protein Tyrosine Phosphatases as Mediators of Redox Signaling (pages 197–206)

      Dr Jeroen den Hertog

    10. Chapter 9

      Hypoxia-Induced Gene Regulation through Hypoxia Inducible Factor-1α (pages 207–227)

      Adam J. Case and Frederick E. Domann

    11. Chapter 10

      Eicosanoid-Based Signaling (pages 229–244)

      Valerie B. O'Donnell

    12. Chapter 11

      Redox-Controlled Transcription Factors and Gene Expression (pages 245–270)

      Gregory I. Giles

    13. Chapter 12

      Nitric Oxide Regulation in Redox Signaling (pages 271–291)

      Dario A. Vitturi, Dr David M. Krzywanski, Edward M. Postlethwait and Dr Rakesh P. Patel

    14. Chapter 13

      Is Hydrogen Sulfide a Regulator of Nitric Oxide Bioavailability in the Vasculature? (pages 293–316)

      Dr. Matthew Whiteman and Philip K. Moore

    15. Chapter 14

      Aspects of Nox/Duox Signaling (pages 317–349)

      Dr Masuko Ushio-Fukai

    16. Chapter 15

      Photodynamic Therapy with Aminolevulinic Acid and Iron Chelators: A Clinical Example of Redox Signaling (pages 351–372)

      Dr Andrew Pye, Yuktee Dogra, Jessica Tyrrell, Prof. Dr. Paul G. Winyard and Alison Curnow

    17. Chapter 16

      Oxidative Stress and Apoptosis (pages 373–383)

      Silvia Cristofanon, Mario Dicato, Lina Ghibelli and Marc Diederich

    18. Chapter 17

      Redox Regulation of Apoptosis in Immune Cells (pages 385–408)

      Edith Charlier, Prof Jacques Piette and Geoffrey Gloire

    19. Chapter 18

      Redox Control in Human Disease with a Special Emphasis on the Peroxiredoxin-Based Antioxidant System (pages 409–431)

      Katalin É. Szabó, Nicholas J. Gutowski, Janet E. Holley, Jennifer A. Littlechild and Prof. Dr. Paul G. Winyard

    20. Chapter 19

      Free Radicals and Mammalian Aging (pages 433–472)

      Dr Alberto Sanz, Gustavo Barja, Reinald Pamplona and Dr Christiaan Leeuwenburgh

    21. You have free access to this content
      Index (pages 473–481)

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