Adipose Tissue in Health and Disease

Copyright © 2010 Wiley-VCH Verlag GmbH & Co. KGaA

Adipose Tissue in Health and Disease

Editor(s): Todd Leff, James G. Granneman

Published Online: 16 APR 2010

Print ISBN: 9783527318575

Online ISBN: 9783527629527

DOI: 10.1002/9783527629527

About this Book

This timely and most comprehensive reference available on the topic covers all the different aspects vital in the fight against the global obesity epidemic.
Following a look at adipose tissue development and morphology, the authors go on to examine its metabolic and endocrine functions and its role in disease. The final section deals with comparative and evolutionary aspects of the tissue.
The result is an essential resource for cell and molecular biologists, physiologists, biochemists, pharmacologists, and those working in the pharmaceutical industry.

Table of contents

    1. You have free access to this content
      Front Matter (pages i–xxv)

  2. Part One: Adipose Tissue Development and Morphology

    1. Chapter 1

      Transcriptional Control of Adipogenesis and Fat Cell Gene Expression (pages 1–20)

      Ursula A. White and Jacqueline M. Stephens

    2. Chapter 2

      Cellular and Molecular Basis of Functional Differences among Fat Depots (pages 21–47)

      Thomas Thomou, Tamara Tchkonia and James L. Kirkland

    3. Chapter 3

      Plasticity of the Adipose Organ (pages 49–67)

      Saverio Cinti

    4. Chapter 4

      Biology of Adipose Tissue Stem Cells (pages 69–80)

      Jeffrey M. Gimble, Bruce A. Bunnell and Farshid Guilak

  3. Part Two: Metabolic Functions of Adipose Tissue

    1. Chapter 5

      Molecular Mechanisms of Adipocyte Lipolysis (pages 81–96)

      James G. Granneman and Hsiao-Ping H. Moore

    2. Chapter 6

      New Developments in the Lipolytic Processing of Triglyceride-Rich Lipoproteins (pages 97–108)

      André Bensadoun, Anne P. Beigneux, Loren G. Fong and Stephen G. Young

    3. Chapter 7

      Intracellular Fatty Acid Transport, Activation, and Trafficking (pages 109–127)

      Doug Mashek

    4. Chapter 8

      Aquaporins and Adipose Tissue: Lesson from Discovery to Physiopathology and to the Clinic of Aquaporin Adipose (AQP7) (pages 129–147)

      Ken Kishida

    5. Chapter 9

      Signaling Pathways Controlling Lipolysis and Lipid Mobilization in Humans (pages 149–179)

      Max Lafontan

  4. Part Three: Endocrine Functions of Adipose Tissue

    1. Chapter 10

      Leptin Secretion and Action (pages 181–199)

      Robert V. Considine

    2. Chapter 11

      Adiponectin (pages 201–230)

      Jonathan P. Whitehead and Ayanthi A. Richards

    3. Chapter 12

      Preadipocyte Factor-1 and Adipose Tissue-Specific Secretory Factor/Resistin – Two Secreted Factors from Adipose Tissue: Role in Adipogenesis and Insulin Resistance (pages 231–243)

      Hei Sook Sul, Yuhui Wang and Carolyn Hudak

    4. Chapter 13

      Adipose Tissue and Blood Pressure Regulation (pages 245–263)

      Lisa A. Cassis and Sara B. Police

    5. Chapter 14

      Adipokines, Inflammation, and Obesity (pages 265–281)

      Karine Clément

  5. Part Four: Adipose Tissue and Disease

    1. Chapter 15

      Depot-Specific Biology of Adipose Tissues: Links to Fat Distribution and Metabolic Risk (pages 283–306)

      Mi-Jeong Lee and Susan K. Fried

    2. Chapter 16

      Viral Induction of Obesity and Adipogenesis (pages 307–332)

      Magdalena Pasarica, Rohan N. Dhurandhar, Nazar Mashtalir and Nikhil V. Dhurandhar

    3. Chapter 17

      Adipose Tissue Cachexia (pages 333–345)

      Michael John Tisdale

    4. Chapter 18

      Obesity and Diabetes: Lipotoxicity (pages 347–368)

      Christopher J. Lelliott, Matej Orešič and Antonio J. Vidal-Puig

    5. Chapter 19

      Obesity and Cancer (pages 369–384)

      Andrew G. Renehan

    6. Chapter 20

      Overview of Acquired and Genetic Lipodystrophies (pages 385–402)

      Tisha Joy and Robert A. Hegele

    7. Chapter 21

      Mouse Models of Lipodystrophy (pages 403–422)

      Jimmy Donkor and Karen Reue

    8. Chapter 22

      Caloric Restriction, Longevity, and Adiposity (pages 423–439)

      Leanne M. Redman and Eric Ravussin

    9. Chapter 23

      Peroxisome Proliferator-Activated Receptor-γ: A Key Regulator of Adipose Tissue Formation, Remodeling, and Metabolism (pages 441–458)

      Olga Astapova and Todd Leff

    10. Chapter 24

      Early-Life Programming of Adipogenesis and Adiposity (pages 459–472)

      Roselle L. Cripps and Susan E. Ozanne

    11. Chapter 25

      Evolutionary Aspects of Obesity and Adipose Tissue Function (pages 473–490)

      Jonathan C. K. Wells

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      Index (pages 491–504)

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