Medical Biostatistics for Complex Diseases
Copyright © 2010 Wiley-VCH Verlag GmbH & Co. KGaA
Editor(s): Frank Emmert-Streib, Matthias Dehmer
Published Online: 19 JUL 2010
Print ISBN: 9783527325856
Online ISBN: 9783527630332
About this Book
A collection of highly valuable statistical and computational approaches designed for developing powerful methods to analyze large-scale high-throughput data derived from studies of complex diseases. Such diseases include cancer and cardiovascular disease, and constitute the major health challenges in industrialized countries. They are characterized by the systems properties of gene networks and their interrelations, instead of individual genes, whose malfunctioning manifests in pathological phenotypes, thus making the analysis of the resulting large data sets particularly challenging. This is why novel approaches are needed to tackle this problem efficiently on a systems level. Written by computational biologists and biostatisticians, this book is an invaluable resource for a large number of researchers working on basic but also applied aspects of biomedical data analysis emphasizing the pathway level.