Ideas in Chemistry and Molecular Sciences: Where Chemistry Meets Life

Copyright © 2010 Wiley-VCH Verlag GmbH & Co. KGaA

Ideas in Chemistry and Molecular Sciences: Where Chemistry Meets Life

Editor(s): Bruno Pignataro

Published Online: 9 JUN 2010

Print ISBN: 9783527325412

Online ISBN: 9783527630516

DOI: 10.1002/9783527630516

About this Book

Product Information

About The Product

Ideas in Chemistry and Molecular Sciences gives an account of the most recent results of research in life sciences in Europe based on a selection of leading young scientists participating in the 2008 European Young Chemists Award competition. In addition to this, the authors provide the state of the art of their field of research and the perspective or preview of future directions.

Table of contents

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      Front Matter (pages I–XXI)

  2. Part I: Biochemical Studies

    1. Chapter 1

      The Role of Copper Ion and the Ubiquitin System in Neurodegenerative Disorders (pages 1–30)

      Fabio Arnesano

    2. Chapter 2

      The Bioinorganic and Organometallic Chemistry of Copper(III) (pages 31–57)

      Xavi Ribas and Alicia Casitas

    3. Chapter 3

      Chemical Protein Modification (pages 59–91)

      Gonçalo J. L. Bernardes, Justin M. Chalker and Benjamin G. Davis

  3. Part II: Drug Delivery

    1. Chapter 4

      Vitamin B12: A Potential Targeting Molecule for Therapeutic Drug Delivery (pages 93–115)

      Pilar Ruiz-Sánchez

    2. Chapter 5

      Strategies for Microsphere-Mediated Cellular Delivery (pages 117–140)

      Rosario M. Sanchez-Martin, Lois M. Alexander, Juan Manuel Cardenas-Maestre and Mark Bradley

  4. Part III: Research in Therapeutics

    1. Chapter 6

      Fundamental Processes in Radiation Damage to DNA: How Low-Energy Electrons Damage Biomolecules (pages 141–165)

      Ilko Bald

    2. Chapter 7

      Structure-Based Design on the Way to New Anti-Infectives (pages 167–190)

      Anna Katharina Herta Hirsch

    3. Chapter 8

      Drug–Membrane Interactions: Molecular Mechanisms Underlying Therapeutic and Toxic Effects of Drugs (pages 191–214)

      Marlene Lúcio, José L. F. C. Lima and Salette Reis

    4. Chapter 9

      Targeting Disease with Small Molecule Inhibitors of Protein–Protein Interactions (pages 215–238)

      Fedor Forafonov, Elena Miranda, Ida Karin Nordgren and Ali Tavassoli

    5. Chapter 10

      Cracking the Glycocode: Recent Developments in Glycomics (pages 239–263)

      Lars Hillringhaus and Jürgen Seibel

  5. Part IV: Enzyme Chemistry

    1. Chapter 11

      O2 Reactivity at Model Copper Systems: Mimicking Tyrosinase Activity (pages 265–289)

      Anna Company

  6. Part V: Structure–Property Relationship and Biosensing

    1. Chapter 12

      Chirality in Biochemistry: A Computational Approach for Investigating Biomolecule Conformations (pages 291–312)

      Adriana Pietropaolo

    2. Chapter 13

      Collisional Mechanism–Based E-DNA Sensors: A General Platform for Label-Free Electrochemical Detection of Hybridization and DNA Binding Proteins (pages 313–326)

      Francesco Ricci

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      Index (pages 327–335)

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