Amino Acids, Peptides and Proteins in Organic Chemistry: Building Blocks, Catalysis and Coupling Chemistry, Volume 3

Amino Acids, Peptides and Proteins in Organic Chemistry: Building Blocks, Catalysis and Coupling Chemistry, Volume 3

Editor(s): Andrew B. Hughes

Published Online: 31 JAN 2011 03:13PM EST

Print ISBN: 9783527321025

Online ISBN: 9783527631803

DOI: 10.1002/9783527631803

About this Book

This is the third of five books in the Amino Acids, Peptides and Proteins in Organic Synthesis series. 

Closing a gap in the literature, this is the only series to cover this important topic in organic and biochemistry. Drawing upon the combined expertise of the international "who's who" in amino acid research, these volumes represent a real benchmark for amino acid chemistry, providing a comprehensive discussion of the occurrence, uses and applications of amino acids and, by extension, their polymeric forms, peptides and proteins.

The practical value of each volume is heightened by the inclusion of experimental procedures.

 

The 5 volumes cover the following topics:

Volume 1: Origins and Synthesis of Amino Acids

Volume 2: Modified Amino Acids, Organocatalysis and Enzymes

Volume 3: Building Blocks, Catalysis and Coupling Chemistry

Volume 4: Protection Reactions, Medicinal Chemistry, Combinatorial Synthesis

Volume 5: Analysis and Function of Amino Acids and Peptides

 

This third volume in the series presents an in depth account of recent developments in the (bio-)synthesis of amino acids and peptides. Divided into two parts, the first section deals with amino acids as building blocks, including the generation of alpha-amino acids, beta-lactams, and heterocycles. The second section is devoted to the synthesis of peptides, with the focus on solid phase synthesis. However, solution phase peptide synthesis is covered as well, as are topics such as coupling reagents, chemical ligation, peptide purification and automation.

 

Originally planned as a six volume series, Amino Acids, Peptides and Proteins in Organic Chemistry now completes with five volumes but remains comprehensive in both scope and coverage.

Further information about the 5 Volume Set and purchasing details can be viewed here.

Table of contents

    1. You have free access to this content
  1. Part One: Amino Acids as Building Blocks

    1. Chapter 4

      Synthesis of β-Lactams (Cephalosporins) by Bioconversion (pages 143–167)

      José Luis Barredo, Marta Rodriguez-Sáiz, José Luis Adrio and Arnold L. Demain

  2. Part Two: Amino Acid Coupling Chemistry

    1. Chapter 15

      Peptide Purification by Reversed-Phase Chromatography (pages 519–548)

      Ulrike Kusebauch, Joshua McBee, Julie Bletz, Richard J. Simpson and Robert L. Moritz

    2. Chapter 16

      Difficult Peptides (pages 549–569)

      M. Terêsa Machini Miranda, Cleber W. Liria and Cesar Remuzgo

    1. You have free access to this content

SEARCH