Amino Acids, Peptides and Proteins in Organic Chemistry: Protection Reactions, Medicinal Chemistry, Combinatorial Synthesis, Volume 4

Amino Acids, Peptides and Proteins in Organic Chemistry: Protection Reactions, Medicinal Chemistry, Combinatorial Synthesis, Volume 4

Editor(s): Andrew B. Hughes

Published Online: 7 APR 2011 10:39AM EST

Print ISBN: 9783527321032

Online ISBN: 9783527631827

DOI: 10.1002/9783527631827

About this Book

This is the fourth of five books in the Amino Acids, Peptides and Proteins in Organic Synthesis series. 

Closing a gap in the literature, this is the only series to cover this important topic in organic and biochemistry. Drawing upon the combined expertise of the international "who's who" in amino acid research, these volumes represent a real benchmark for amino acid chemistry, providing a comprehensive discussion of the occurrence, uses and applications of amino acids and, by extension, their polymeric forms, peptides and proteins.

The practical value of each volume is heightened by the inclusion of experimental procedures.

 

The 5 volumes cover the following topics:

Volume 1: Origins and Synthesis of Amino Acids

Volume 2: Modified Amino Acids, Organocatalysis and Enzymes

Volume 3: Building Blocks, Catalysis and Coupling Chemistry

Volume 4: Protection Reactions, Medicinal Chemistry, Combinatorial Synthesis

Volume 5: Analysis and Function of Amino Acids and Peptides

 

The fourth volume in this series is structured in three main sections. The first section is about protection reactions and amino acid based peptidomimetics. The second, and most extensive, part is devoted to the medicinal chemistry of amino acids. It includes, among others, the chemistry of alpha- and beta amino acids, peptide drugs, and advances in N- and O-glycopeptide synthesis. The final part deals with amino acids in combinatorial synthesis. Methods, such as phage display, library peptide synthesis, and computational design are described.

 

Originally planned as a six volume series, Amino Acids, Peptides and Proteins in Organic Chemistry now completes with five volumes but remains comprehensive in both scope and coverage.

Further information about the 5 Volume Set and purchasing details can be viewed here.

Table of contents

    1. You have free access to this content
    1. Chapter 1

      Protection Reactions (pages 1–97)

      Vommina V. Sureshbabu and Narasimhamurthy Narendra

  1. Part One: Amino Acid-Based Peptidomimetics

  2. Part Two: Medicinal Chemistry of Amino Acids

    1. Chapter 7

      Peptide Drugs (pages 247–275)

      Chiara Falciani, Alessandro Pini and Luisa Bracci

    2. Chapter 8

      Oral Bioavailability of Peptide and Peptidomimetic Drugs (pages 277–292)

      Arik Dahan, Yasuhiro Tsume, Jing Sun, Jonathan M. Miller and Gordon L. Amidon

  3. Part Three: Amino Acids in Combinatorial Synthesis

    1. Chapter 13

      Phage-Displayed Combinatorial Peptides (pages 451–471)

      Renhua Huang, Kritika Pershad, Malgorzata Kokoszka and Brian K. Kay

    2. Chapter 15

      Amino Acid-Based Dendrimers (pages 491–517)

      Zhengshuang Shi, Chunhui Zhou, Zhigang Liu, Filbert Totsingan and Neville R. Kallenbach

    1. You have free access to this content

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