Prodrugs and Targeted Delivery: Towards Better ADME Properties
Copyright © 2011 Wiley-VCH Verlag GmbH & Co. KGaA
Editor(s): Jarkko Rautio
Published Online: 4 APR 2011 01:43PM EST
Print ISBN: 9783527326037
Online ISBN: 9783527633166
Book Series: Methods and Principles in Medicinal Chemistry
Series Editor(s): Raimund Mannhold, Hugo Kubinyi, Gerd Folkers
About this Book
This topical reference and handbook addresses the chemistry, pharmacology, toxicology and the patentability of prodrugs, perfectly mirroring the integrated approach prevalent in today's drug design. It summarizes current experiences and strategies for the rational design of prodrugs, beginning at the early stages of the development process, as well as discussing organ- and site-selective prodrugs.
Every company employing medicinal chemists will be interested in this practice-oriented overview of a key strategy in modern drug discovery and development.