Antiviral Drug Strategies

Antiviral Drug Strategies

Editor(s): Erik De Clercq

Published Online: 12 MAY 2011 09:12AM EST

Print ISBN: 9783527326969

Online ISBN: 9783527635955

DOI: 10.1002/9783527635955

Series Editor(s): Raimund Mannhold, Hugo Kubinyi, Gerd Folkers

About this Book

By focusing on general molecular mechanisms of antiviral drugs rather than therapies for individual viruses, this ready reference provides the critical knowledge needed to develop entirely novel therapeutics and to target new viruses.
It begins with a general discussion of antiviral strategies, followed by a broad survey of known viral targets, such as reverse transcriptases, proteases, neuraminidases, RNA polymerases, helicases and primases, as well as their known inhibitors. The final section contains several cases studies of recent successful antiviral drug development.
Edited by Erik de Clercq, the world authority on small molecule antiviral drugs, who has developed more new antivirals than anyone else.

Table of contents

    1. You have free access to this content
    2. Chapter 7

      Cyclophilin Inhibitors (pages 147–180)

      Grégoire Vuagniaux, Arnaud Hamel, Rafael Crabbé, Hervé C. Porchet and Jean-Maurice Dumont

    3. Chapter 14

      Neuraminidase Inhibitors as Anti-Influenza Agents (pages 351–376)

      Willard Lew, Michael Z. Wang, Xiaowu Chen, James F. Rooney and Choung Kim

    4. You have free access to this content