Melanins and Melanosomes: Biosynthesis, Biogenesis, Physiological, and Pathological Functions
Copyright © 2011 Wiley-VCH Verlag GmbH & Co. KGaA
Editor(s): Jan Borovanský, Patrick A. Riley
Published Online: 27 JUL 2011 06:54AM EST
Print ISBN: 9783527328925
Online ISBN: 9783527636150
About this Book
The surface pigmentation of vertebrates is controlled by specialized cells able to synthesize a variety of pigments collectively known as melanins. Recent research has shown that melanins are produced not only in the skin but also in many other sites such as the eye, inner ear, muscles, etc., - where they are engaged in some unanticipated roles. The details of the synthetic pathway, the complexities of its regulation and biological significance that have been unravelled in recent research comprise a fascinating story and are of key importance in understanding the nature of diseases, including malignant melanoma one of the most rapidly spreading cancers.