NMR of Biomolecules: Towards Mechanistic Systems Biology

NMR of Biomolecules: Towards Mechanistic Systems Biology

Editor(s): Ivano Bertini, Kathleen S. McGreevy, Giacomo Parigi

Published Online: 21 MAR 2012

Print ISBN: 9783527328505

Online ISBN: 9783527644506

DOI: 10.1002/9783527644506

About this Book

NMR is one of the most powerful methods for imaging of biomolecules. This book is the ultimate NMR guide for researchers in the biomedical community and gives not only background and practical tips but also a forward looking view on the future of NMR in systems biology.

Table of contents

    1. You have free access to this content
  1. Part One: Introduction

    1. Chapter 1

      NMR and its Place in Mechanistic Systems Biology (pages 1–5)

      Prof. Dr. Ivano Bertini, Kathleen S. McGreevy and Prof. Giacomo Parigi

    2. Chapter 2

      Structure of Biomolecules: Fundamentals (pages 7–32)

      Lucia Banci, Francesca Cantini, Mirko Cevec, Hendrik R. A. Jonker, Senada Nozinovic, Christian Richter and Harald Schwalbe

  2. Part Two: Role of NMR in the Study of the Structure and Dynamics of Biomolecules

    1. Chapter 6

      RNA (pages 118–135)

      Richard Štefl and Vladimír Sklenář

    2. Chapter 8

      Paramagnetic Molecules (pages 154–171)

      Ivano Bertini, Claudio Luchinat and Giacomo Parigi

  3. Part Three: Role of NMR in the Study of the Structure and Dynamics of Biomolecular Interactions

    1. Chapter 12

      Protein–RNA Interactions (pages 218–236)

      Vijayalaxmi Manoharan, Jose Manuel Pérez-Cañadillas and Andres Ramos

  4. Part Four: NMR in Drug Discovery

    1. Chapter 17

      RNA as a Drug Target (pages 298–313)

      Jan-Peter Ferner, Elke Duchardt Ferner, Jörg Rinnenthal, Janina Buck, Jens Wöhnert and Harald Schwalbe

    2. Chapter 19

      NMR of Peptides (pages 328–344)

      Johannes G. Beck, Andreas O. Frank and Horst Kessler

  5. Part Five: Solid-State NMR

    1. Chapter 22

      Microcrystalline Proteins – An Ideal Benchmark for Methodology Development (pages 376–392)

      W. Trent Franks, Barth-Jan van Rossum, Benjamin Bardiaux, Enrico Ravera, Giacomo Parigi, Claudio Luchinat and Hartmut Oschkinat

  6. Part Six: Frontiers in NMR Spectroscopy

    1. Chapter 29

      In-Cell Protein NMR Spectroscopy (pages 478–494)

      David S. Burz, David Cowburn, Kaushik Dutta and Alexander Shekhtman

    2. Chapter 30

      Structural Investigation of Cell-Free Expressed Membrane Proteins (pages 496–508)

      Solmaz Sobhanifar, Sina Reckel, Frank Löhr, Frank Bernhard and Volker Dötsch

  7. Part Seven: Computational Aspects

    1. Chapter 32

      Protein–Protein Docking with HADDOCK (pages 520–535)

      Christophe Schmitz, Adrien S. J. Melquiond, Sjoerd J. de Vries, Ezgi Karaca, Marc van Dijk, Panagiotis L. Kastritis and Alexandre M. J. J. Bonvin

    1. You have free access to this content
    1. You have free access to this content

SEARCH