Analogue-Based Drug Discovery III

Analogue-Based Drug Discovery III

Editor(s): János Fischer, C. Robin Ganellin, David P. Rotella

Published Online: 18 DEC 2012 11:37AM EST

Print ISBN: 9783527330737

Online ISBN: 9783527651085

DOI: 10.1002/9783527651085

About this Book

Most drugs are analogue drugs. There are no general rules how a new drug can be discovered, nevertheless, there are some observations which help to find a new drug, and also an individual story of a drug discovery can initiate and help new discoveries. Volume III is a continuation of the successful book series with new examples of established and recently introduced drugs.
The major part of the book is written by key inventors either as a case study or a study of an analogue class. With its wide range across a variety of therapeutic fields and chemical classes, this is of interest to virtually every researcher in drug discovery and pharmaceutical chemistry, and -- together with the previous volumes -- constitutes the first systematic approach to drug analogue development.

Table of contents

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  1. Part I: General Aspects

    1. Chapter 1

      Pioneer and Analogue Drugs (pages 1–19)

      Prof. Dr. János Fischer, Prof. Dr. C. Robin Ganellin and Prof. Dr. David P. Rotella

  2. Part II: Drug Classes

  3. Part III: Case Studies

    1. Chapter 10

      The Discovery of Dabigatran Etexilate (pages 241–267)

      Norbert Hauel, Andreas Clemens, Herbert Nar, Henning Priepke, Joanne van Ryn and Wolfgang Wienen

    2. Chapter 13

      Novel Taxanes: Cabazitaxel Case Study (pages 319–341)

      Dr. Hervé Bouchard, Dr. Dorothée Semiond, Dr. Marie-Laure Risse and Dr. Patricia Vrignaud

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