Amyloid Fibrils and Prefibrillar Aggregates: Molecular and Biological Properties
Copyright © 2013 Wiley-VCH Verlag GmbH & Co. KGaA
Editor(s): Daniel Erik Otzen
Published Online: 27 JAN 2013 05:03AM EST
Print ISBN: 9783527332007
Online ISBN: 9783527654185
DOI: 10.1002/9783527654185
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Summing up almost a decade of biomedical research, this topical and eagerly awaited handbook is the first reference on the topic to incorporate recent breakthroughs in amyloid research.
The first part covers the structural biology of amyloid fibrils and pre-fibrillar assemblies, including a description of current models for amyloid formation. The second part looks at the diagnosis and biomedical study of amyloid in humans and in animal models, while the final section discusses pharmacological approaches to manipulating amyloid and also looks at its physiological roles in lower and higher organisms.