Comprehensive Enantioselective Organocatalysis: Catalysts, Reactions, and Applications

Comprehensive Enantioselective Organocatalysis: Catalysts, Reactions, and Applications

Editor(s): Peter I. Dalko

Published Online: 23 AUG 2013 09:12PM EST

Print ISBN: 9783527332366

Online ISBN: 9783527658862

DOI: 10.1002/9783527658862

About this Book

Structured in three parts this manual recollects efficient organocatalytic transformations around clear principles that meet actual standard in asymmetric synthesis. Chapters were written by acknowledged leaders of the organocatalysis field, and are presented in a concise way. Volume 1: Privileged Catalysts gives insight to readers to the continuously increasing variety of catalysts, and the relatively complex interactions that make organocatalytic reactions selective. An appendix recollects catalyst structures with the adequate cross-references. Volume 2: Activations covers the fundamental activation types (non-covalent and covalent activations) and helps understanding the importance of physical parameters, and in particular, the role of water, that influences reactivity and selectivity. Volume 3: Reactions and Applications highlights transformations by reaction types. The final part of this volume is dedicated to application in multistep synthesis and industrial applications.

Considering the ever increasing interest in the organocatalysis field, the book aims addressing to a large audience: to academic, and, industrial researchers, students and teachers who are interested in synthetic organic chemistry at advanced level. This book provides non-specialists with an introduction to the topic as well as serving as a valuable source for newcomers and researchers searching for an up-to-date and comprehensive overview of this promising area of synthetic organic chemistry.

Table of contents

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  1. Part I: Amino Acid-Derived Catalysts

    1. Chapter 2

      TMS-Prolinol Catalyst in Organocatalysis (pages 33–50)

      Hao Jiang, Łukasz Albrecht, Gustav Dickmeiss, Kim L. Jensen and Karl Anker Jørgensen

  2. Part II: Non-Amino Acid-Derived Catalysts

    1. Chapter 7

      Chiral C2 Catalysts (pages 161–193)

      Daisuke Uraguchi, Kohsuke Ohmatsu and Takashi Ooi

    2. Chapter 9

      Dynamic Approaches towards Catalyst Discovery (pages 221–237)

      Patrizia Galzerano, Giulio Gasparini, Marta Dal Molin and Leonard J. Prins

  3. Part I: Asymmetric Catalysis with Non-Covalent Interactions

    1. Chapter 10

      Brønsted Acids (pages 239–288)

      Yunus E. Türkmen, Ye Zhu and Viresh H. Rawal

  4. Part II: Asymmetric Catalysis with Covalent Interactions

    1. Chapter 18

      Carbene Catalysts (pages 495–522)

      Karen Thai, Eduardo Sánchez-Larios and Michel Gravel

  5. Part III: Tuning Catalyst Activity and Selectivity by the Reaction Medium and Conditions

    1. Chapter 22

      Ionic Liquid Organocatalysts (pages 617–650)

      Dmitry E. Siyutkin, Alexander S. Kucherenko and Sergei G. Zlotin

  6. Part I: Alpha-Alkylation and Heteroatom Functionalization

    1. Chapter 26

      Alpha-Alkylation by SN1-Type Reactions (pages 729–755)

      Andrea Gualandi, Diego Petruzziello, Enrico Emer and Pier Giorgio Cozzi

  7. Part II: Nucleophile Addition to C=X Bonds

  8. Part III: Nucleophile Addition to C=C Bonds

  9. Part IV: Ring-Forming Reactions

  10. Part V: Increasing Complexity

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    1. You have free access to this content