Cascade Biocatalysis : Integrating Stereoselective and Environmentally Friendly Reactions

Cascade Biocatalysis : Integrating Stereoselective and Environmentally Friendly Reactions

Editor(s): Sergio Riva, Wolf-Dieter Fessner

Published Online: 27 JUN 2014 08:31PM EST

Print ISBN: 9783527335220

Online ISBN: 9783527682492

DOI: 10.1002/9783527682492

About this Book

This ready reference presents environmentally friendly and stereoselective methods of modern biocatalysis.
The experienced and renowned team of editor have gathered top international authors for this book. They cover such emerging topics as chemoenzymatic methods and multi-step enzymatic reactions, while showing how these novel methods and concepts can be used for practical applications. Multidisciplinary topics, including directed evolution, dynamic kinetic resolution, and continuous-flow methodology are also discussed.

From the contents:
- Directed evolution of ligninolytic oxidoreductases: from functional expression to stabilization
- New trends in the in situ enzymatic recycling of NAD(P)(H) cofactor
- Redox Cascade Biotransformations
- Chemistry and Biochemistry synergies for ß-amino acids production
- Dynamic kinetic resolution of amino acid thioesters
- Stereoselective hydrolase-catalyzed processes in continuous-flow mode
- Perspectives on multi-enzyme processes
- Nitrile converting enzymes involved in natural and synthetic cascade reactions
- Mining genomes for nitrilases
- Kinetic aspects of the in-situ NHase/AMase cascade system of M. imperiale resting cells for nitrile bioconversion
- Stereoselective hydrolysis of beta substituted nitriles
- New applications of Transketolase
- Enzymatic generation of sialoconjugate diversity
- Methyltransferases in biocatalysis

Table of contents

    1. You have free access to this content
    2. Chapter 1

      Directed Evolution of Ligninolytic Oxidoreductases: from Functional Expression to Stabilization and Beyond (pages 1–22)

      Eva Garcia-Ruiz, Diana M. Mate, David Gonzalez-Perez, Patricia Molina-Espeja, Susana Camarero, Angel T. Martínez, Antonio O. Ballesteros and Miguel Alcalde

    3. Chapter 7

      Synergies of Chemistry and Biochemistry for the Production of β-Amino Acids (pages 161–178)

      Josefa María Clemente-Jiménez, Sergio Martínez-Rodríguez, Felipe Rodríguez-Vico and Francisco Javier Las Heras-Vázquez

    4. Chapter 11

      Nitrile Converting Enzymes Involved in Natural and Synthetic Cascade Reactions (pages 249–270)

      Ludmila Martínková, Andreas Stolz, Fred van Rantwijk, Nicola D'Antona, Dean Brady and Linda G. Otten

    5. Chapter 17

      Enzymatic Generation of Sialoconjugate Diversity (pages 361–392)

      Wolf-Dieter Fessner, Ning He, Dong Yi, Peter Unruh and Marion Knorst

    6. Chapter 18

      Methyltransferases in Biocatalysis (pages 393–426)

      Ludger Wessjohann, Martin Dippe, Martin Tengg and Mandana Gruber-Khadjawi

    7. You have free access to this content