Brief Research Communication
Location of the handedness gene on the X and Y chromosomes
Article first published online: 6 DEC 1998
Copyright © 1996 Wiley-Liss, Inc.
American Journal of Medical Genetics
Volume 67, Issue 1, pages 50–52, 16 February 1996
How to Cite
Corballis, M. C., Lee, K., McManus, I. C. and Crow, T. J. (1996), Location of the handedness gene on the X and Y chromosomes. Am. J. Med. Genet., 67: 50–52. doi: 10.1002/(SICI)1096-8628(19960216)67:1<50::AID-AJMG8>3.0.CO;2-W
- Issue published online: 24 OCT 2002
- Article first published online: 6 DEC 1998
- Manuscript Revised: 12 MAY 1995
- Manuscript Received: 28 NOV 1994
- X chromosome;
- Y chromosome;
Accumulated data from five handedness surveys show that concordance for sex is slightly but reliably higher among siblings of the same handedness than among those of opposite handedness. This is consistent with Crow's theory that the genetic locus for handedness is in an X-Y homologous region of the sex chromosomes. The small size of the effect is predicted from genetic models in which there is a substantial random component underlying phenotypic left handedness. The findings are relevant to the putative role of cerebral asymmetry in the aetiology of psychosis. © 1996 Wiley-Liss, Inc.