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Serotonin transporter gene (5-HTT) polymorphisms and compulsive buying
Article first published online: 16 MAR 1999
DOI: 10.1002/(SICI)1096-8628(19990416)88:2<123::AID-AJMG5>3.0.CO;2-S
Copyright © 1999 Wiley-Liss, Inc.
1552-4833/asset/cover.gif?v=1&s=9818ec8c89d0772bf0e752b15694c460afb83f9f "American Journal of Medical Genetics")
Additional Information
How to Cite
Devor, E. J., Magee, H. J., Dill-Devor, R. M., Gabel, J. and Black, D. W. (1999), Serotonin transporter gene (5-HTT) polymorphisms and compulsive buying. American Journal of Medical Genetics, 88: 123–125. doi: 10.1002/(SICI)1096-8628(19990416)88:2<123::AID-AJMG5>3.0.CO;2-S
Publication History
- Issue published online: 25 OCT 2002
- Article first published online: 16 MAR 1999
- Manuscript Received: 11 MAR 1998
- Manuscript Accepted: 11 MAR 1998
Funded by
- Solvay Pharmaceuticals
- Pharmacia-Upjohn Pharmaceuticals
- Abstract
- References
- Cited By
Keywords:
- impulse control;
- molecular genetics;
- association study
Abstract
We examined a panel of 21 patients diagnosed with compulsive buying for two DNA sequence polymorphisms found in the gene that encodes the serotonin transport (5-HTT). One polymorphism, found in the promoter region of the 5-HTT gene, involves a 44-base pair (bp) deletion, and the other, found in the second intron, is due to variable numbers of a repeat sequence. We also typed a panel of 38 psychiatrically normal controls for both 5-HH markers. When compared to this control panel, no significant differences were seen for either 5-HTT marker among the compulsive buyers. Am. J. Med. Genet. (Neuropsychiatr. Genet.) 88:123–125 1999.© 1999 Wiley-Liss, Inc.