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Brief Report
Exclusion of the stomatin, α-adducin and β-adducin loci in a large kindred with dehydrated hereditary stomatocytosis
Article first published online: 29 JAN 1999
DOI: 10.1002/(SICI)1096-8652(199901)60:1<72::AID-AJH13>3.0.CO;2-8
Copyright © 1999 Wiley-Liss, Inc.
1096-8652/asset/cover.gif?v=1&s=d31a603f9c7a1894ee3b68044c6fdcbe64ff8068 "American Journal of Hematology")
Additional Information
How to Cite
Innes, D. S., Sinard, J. H., Gilligan, D. M., Snyder, L. M., Gallagher, P. G. and Morrow, J. S. (1999), Exclusion of the stomatin, α-adducin and β-adducin loci in a large kindred with dehydrated hereditary stomatocytosis. American Journal of Hematology, 60: 72–74. doi: 10.1002/(SICI)1096-8652(199901)60:1<72::AID-AJH13>3.0.CO;2-8
Publication History
- Issue published online: 29 JAN 1999
- Article first published online: 29 JAN 1999
- Manuscript Accepted: 12 AUG 1998
- Manuscript Received: 2 JUN 1998
Funded by
- National Institutes of Health
- March of Dimes Birth Defects Foundation
- Children's Clinical Research Center, Yale University School of Medicine
- Department of Hospital Lab Educational fund, University of Massachusetts Medical Center
- Abstract
- References
- Cited By
Keywords:
- stomatocytosis;
- erythrocytes;
- linkage analysis;
- stomatin;
- alpha-adducin;
- beta-adducin
Abstract
Defects in stomatin, α-and β-adducin have been implicated in erythrocyte disorders of cation permeability. We performed linkage analysis of the genetic loci for these proteins in a large kindred with xerocytosis (dehydrated hereditary stomatocytosis). Using polymerase chain reaction-based genotyping techniques, all three loci are excluded as disease gene candidates. Am. J. Hematol. 60:72–74, 1999. © 1999 Wiley-Liss, Inc.