Yeast Protein Serine/Threonine Phosphatases: Multiple Roles and Diverse Regulation
Article first published online: 4 DEC 1998
Copyright © 1996 John Wiley & Sons, Ltd.
Volume 12, Issue 16, pages 1647–1675, December 1996
How to Cite
STARK, M. J. R. (1996), Yeast Protein Serine/Threonine Phosphatases: Multiple Roles and Diverse Regulation. Yeast, 12: 1647–1675. doi: 10.1002/(SICI)1097-0061(199612)12:16<1647::AID-YEA71>3.0.CO;2-Q
- Issue published online: 4 DEC 1998
- Article first published online: 4 DEC 1998
- Manuscript Received: 14 AUG 1996
- Wellcome Trust
- protein phosphatase;
Since the isolation of the first yeast protein phosphatase genes in 1989, much progress has been made in understanding this important group of proteins. Yeast contain genes encoding all the major types of protein phosphatase found in higher eukaryotes and the ability to use powerful genetic approaches will complement the wealth of biochemical information available from other systems. This review will summarize recent progress in understanding the structure, function and regulation of the PPP family of protein serine-threonine phosphatases, concentrating on the budding yeast Saccharomyces cerevisiae.