On leave from Institute of Mathematics, Polish Academy of Sciences, Warsaw, Poland.
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Research Article
Criteria for evaluating protein structures derived from comparative modeling
Article first published online: 7 DEC 1998
DOI: 10.1002/(SICI)1097-0134(1997)1+<7::AID-PROT3>3.0.CO;2-O
Copyright © 1998 Wiley-Liss, Inc.
Issue
1097-0134/asset/cover.gif?v=1&s=d817e79b67ba6cacf8bdcce1a819c04de300a7e3 "Proteins: Structure, Function, and Bioinformatics")
Proteins: Structure, Function, and Bioinformatics
Supplement: Supplement 1
Volume 29, Issue Supplement 1, pages 7–13, 1997
Additional Information
How to Cite
Venclovas, Č., Zemla, A., Fidelis, K. and Moult, J. (1997), Criteria for evaluating protein structures derived from comparative modeling. Proteins, 29: 7–13. doi: 10.1002/(SICI)1097-0134(1997)1+<7::AID-PROT3>3.0.CO;2-O
Publication History
- Issue published online: 7 DEC 1998
- Article first published online: 7 DEC 1998
- Manuscript Accepted: 25 AUG 1997
- Manuscript Received: 18 JUL 1997
Funded by
- U.S. Dept. of Energy. Grant Number: W-7405-Eng-48
- Abstract
- References
- Cited By
Keywords:
- comparative modeling;
- homologous modeling;
- protein structure;
- structure prediction
Abstract
Following the first experiment for the Critical Assessment of methods for protein Structure Prediction (CASP1), numerical criteria were devised to analyze the performance of prediction methods. We report here the criteria for comparative modeling, and how effective they were in CASP2. These criteria are intended to evolve into a set of numerical measures that provide a comprehensive assessment of the quality of a structure produced by comparative modeling, and provide a means of investigating which modeling methods are most effective, so as to establish where future effort may be most productively applied. Proteins, Suppl. 1:7–13, 1997. © 1998 Wiley-Liss, Inc.