1097-0134/asset/PROT_centre.gif?v=1&s=77b56b1f2cdaba74cb3bb149bd9b029cd8803cdb)
Numerical Evaluation Method
RMS/Coverage graphs: A qualitative method for comparing three-dimensional protein structure predictions
Article first published online: 8 NOV 1999
DOI: 10.1002/(SICI)1097-0134(1999)37:3+<15::AID-PROT4>3.0.CO;2-Z
Copyright © 1999 Wiley-Liss, Inc.
Issue
1097-0134/asset/cover.gif?v=1&s=d817e79b67ba6cacf8bdcce1a819c04de300a7e3 "Proteins: Structure, Function, and Bioinformatics")
Proteins: Structure, Function, and Bioinformatics
Supplement: Third Meeting on the Critical Assessment of Techniques for Protein Structure Prediction
Volume 37, Issue Supplement 3, pages 15–21, 1999
Additional Information
How to Cite
Hubbard, T. J.P. (1999), RMS/Coverage graphs: A qualitative method for comparing three-dimensional protein structure predictions. Proteins, 37: 15–21. doi: 10.1002/(SICI)1097-0134(1999)37:3+<15::AID-PROT4>3.0.CO;2-Z
Publication History
- Issue published online: 8 NOV 1999
- Article first published online: 8 NOV 1999
- Manuscript Accepted: 14 JUN 1999
- Manuscript Received: 4 JUN 1999
- Abstract
- Article
- References
- Cited By
Keywords:
- protein structure prediction;
- protein structure comparison;
- CASP
Abstract
Evaluating a set of protein structure predictions is difficult as each prediction may omit different residues and different parts of the structure may have different accuracies. A method is described that captures the best results from a large number of alternative sequence-dependent structural superpositions between a prediction and the experimental structure and represents them as a single line on a graph. Applied to CASP2 and CASP3 data the best predictions stand out visually in most cases, as judged by manual inspection. The results from this method applied to CASP data are available from the URLs http://PredictionCenter.llnl.gov/casp3/results/th/ and http://www.sanger.ac.uk/∼th/casp/. Proteins Suppl 1999;3:15–21. © 1999 Wiley-Liss, Inc.