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1097-0134/asset/PROT_centre.gif?v=1&s=77b56b1f2cdaba74cb3bb149bd9b029cd8803cdb)
Numerical Evaluation Method
Processing and analysis of CASP3 protein structure predictions†
Article first published online: 8 NOV 1999
DOI: 10.1002/(SICI)1097-0134(1999)37:3+<22::AID-PROT5>3.0.CO;2-W
Published 1999 Wiley-Liss, Inc.
Issue
1097-0134/asset/cover.gif?v=1&s=d817e79b67ba6cacf8bdcce1a819c04de300a7e3 "Proteins: Structure, Function, and Bioinformatics")
Proteins: Structure, Function, and Bioinformatics
Supplement: Third Meeting on the Critical Assessment of Techniques for Protein Structure Prediction
Volume 37, Issue Supplement 3, pages 22–29, 1999
Additional Information
How to Cite
Zemla, A., Venclovas, Č., Moult, J. and Fidelis, K. (1999), Processing and analysis of CASP3 protein structure predictions. Proteins, 37: 22–29. doi: 10.1002/(SICI)1097-0134(1999)37:3+<22::AID-PROT5>3.0.CO;2-W
- †
Publication History
- Issue published online: 8 NOV 1999
- Article first published online: 8 NOV 1999
- Manuscript Accepted: 15 JUN 1999
- Manuscript Received: 8 JUN 1999
- Abstract
- Article
- References
- Cited By
Keywords:
- prediction evaluation;
- prediction assessment;
- comparative modeling;
- fold recognition;
- ab initio prediction
Abstract
Livermore Prediction Center provides basic infrastructure for the CASP (Critical Assessment of Structure Prediction) experiments, including prediction processing and verification servers, a system of prediction evaluation tools, and interactive numerical and graphical displays. Here we outline the essentials of our approach, with discussion of the superposition procedures, definitions of basic measures, and descriptions of new methods developed to analyze predictions. Our primary focus is on the evaluation of threedimensional models and secondary structure predictions. To put the results of the three prediction experiments held to date on the same footing, the latest CASP3 evaluation criteria were retrospectively applied to both CASP1 and CASP2 predictions. Finally, we give an overview of our website (http://PredictionCenter.llnl.gov), which makes the target structures, predictions, and the evaluation system accessible to the community. Proteins Suppl 1999;3:22–29. Published 1999 Wiley-Liss, Inc.