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Cancer Cytopathology

Cover image for Cancer Cytopathology

25 August 1997

Volume 81, Issue 4

Pages 193–259

Currently known as: Cancer Cytopathology

  1. Contemporary Issues

    1. Top of page
    2. Contemporary Issues
    3. Cytotechnologists Perspectives
    4. Original Articles
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      Applications of fluorescence in situ hybridization techniques in cytopathology (pages 193–197)

      Sandra R. Wolman

      Version of Record online: 10 NOV 2000 | DOI: 10.1002/(SICI)1097-0142(19970825)81:4<193::AID-CNCR1>3.0.CO;2-R

      Fluorescence in situ hybridization can be a valuable adjunct to tumor diagnosis and prognosis. The added value of definition of genetic aberrations in morphologically ambiguous cells should have major advantages for cytopathology.

  2. Cytotechnologists Perspectives

    1. Top of page
    2. Contemporary Issues
    3. Cytotechnologists Perspectives
    4. Original Articles
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      Pap smear risk management by process control (pages 198–211)

      Gary W. Gill

      Version of Record online: 10 NOV 2000 | DOI: 10.1002/(SICI)1097-0142(19970825)81:4<198::AID-CNCR2>3.0.CO;2-M

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      Successfully examining Pap smears requires optimizing and standardizing the sides of the “Cytotect Triangle”: specimen, microscope, and observer. This article describes pertinent aspects of the total process, cites some commonly and uncommonly observed limitations, introduces new concepts, proposes a systematic approach to identifying factors that contribute to false-negative results, and calls for a major reduction in the daily slide-screening workload for cytotechnologists based on total imaging screening coverage as an objective standard of practice.

  3. Original Articles

    1. Top of page
    2. Contemporary Issues
    3. Cytotechnologists Perspectives
    4. Original Articles
    1. Gynecologic Cytopathology
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      Use of statistical analysis of cytologic interpretation to determine the causes of interobserver disagreement and in quality improvement (pages 212–219)

      Andrew A. Renshaw, Kenneth R. Lee and Scott R. Granter

      Version of Record online: 10 NOV 2000 | DOI: 10.1002/(SICI)1097-0142(19970825)81:4<212::AID-CNCR3>3.0.CO;2-R

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      The combination of distribution analysis, kappa statistics, threshold analysis, and receiver operating characteristic curve analysis can distinguish differences in diagnostic accuracy and diagnostic thresholds as causes of variability in cytologic interpretation.

    2. Non-Gynecologic Cytopathology
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      Cytology of germ cell tumors : Extragonadal, extracranial masses and intraoperative puroblems (pages 220–227)

      Michael W. Stanley, Celeste N. Powers, Martha B. Pitman, Soheila Korourian, Ricardo H. Bardales and Kamal Khurana

      Version of Record online: 10 NOV 2000 | DOI: 10.1002/(SICI)1097-0142(19970825)81:4<220::AID-CNCR4>3.0.CO;2-T

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      Specific diagnoses of germ cell neoplasms are essential, because many occur in young patients and are responsive to chemotherapy. Significant differential diagnostic problems are highlighted in this series of 20 cases evaluated in cytologic samples of various types.

    3. Fine-Needle Aspiration
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      Fine-needle aspiration cytopathology of malignant fibrous histiocytoma (pages 228–237)

      Melora D. Berardo, Celeste N. Powers, Paul E. Wakely Jr., Margarida O. Almeida and William J. Frable

      Version of Record online: 10 NOV 2000 | DOI: 10.1002/(SICI)1097-0142(19970825)81:4<228::AID-CNCR5>3.0.CO;2-L

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      This article contains a review of the cytopathology of malignant fibrous histiocytoma and a discussion of the role of fine-needle aspiration biopsy in diagnosing pleomorphic sarcomas.

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      Fine-needle aspiration cytology in tumors and tumor-like conditions of the oral and maxillofacial region : Diagnostic reliability and limitations (pages 238–252)

      Dimitra Daskalopoulou, Alexander D. Rapidis, Nicoletta Maounis and Sophia Markidou

      Version of Record online: 10 NOV 2000 | DOI: 10.1002/(SICI)1097-0142(19970825)81:4<238::AID-CNCR6>3.0.CO;2-L

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      Fine-needle aspiration cytology was used to diagnose 1022 cases of oral and maxillofacial tumors. Analysis of this material showed an overall diagnostic accuracy of 98.2% for this method.

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      Fine-needle aspiration of thyroid nodules : Correlation between cytology and histology and evaluation of discrepant cases (pages 253–259)

      Mary K. Sidawy, David M. Del Vecchio and Stanley M. Knoll

      Version of Record online: 10 NOV 2000 | DOI: 10.1002/(SICI)1097-0142(19970825)81:4<253::AID-CNCR7>3.0.CO;2-Q

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      Indeterminate results and cytodiagnostic errors of thyroid fine-needle aspirations are predominantly due to overlapping cytologic criteria among adenomatoid nodules, follicular neoplasms, and follicular variants of papillary carcinomas. The second major diagnostic pitfall is rendering definite diagnoses on suboptimal FNA samples.

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