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Cancer

Cover image for Cancer

1 September 1998

Volume 83, Issue 5

Pages 825–1060

  1. Cancer—50 Years Later

    1. Top of page
    2. Cancer—50 Years Later
    3. Commentaries
    4. Editorials
    5. Original Articles
    6. Communications
    7. Correspondence
    1. You have free access to this content
      Papillary adenoma of the large intestine : A historical perspective (pages 825–829)

      Robert R. Rickert

      Article first published online: 9 NOV 2000 | DOI: 10.1002/(SICI)1097-0142(19980901)83:5<825::AID-CNCR1>3.0.CO;2-H

      A detailed account of papillary (villous) adenomas of the large intestine appeared in the inaugural volume of Cancer. The current article traces the evolution of our understanding of these tumors and their malignant potential in the five decades since the publication of that 1948 account.

  2. Commentaries

    1. Top of page
    2. Cancer—50 Years Later
    3. Commentaries
    4. Editorials
    5. Original Articles
    6. Communications
    7. Correspondence
    1. You have free access to this content
      Prevention of osteoporosis in women treated for hereditary breast and ovarian carcinoma : A need that is overlooked (pages 830–834)

      Joan M. Lappe and Susan T. Tinley

      Article first published online: 9 NOV 2000 | DOI: 10.1002/(SICI)1097-0142(19980901)83:5<830::AID-CNCR2>3.0.CO;2-M

      Women experiencing estrogen depletion due to cancer treatment should be advised of their increased risk of osteoporosis and receive therapy for its prevention.

  3. Editorials

    1. Top of page
    2. Cancer—50 Years Later
    3. Commentaries
    4. Editorials
    5. Original Articles
    6. Communications
    7. Correspondence
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      Predicting outcomes of therapy for prostate carcinoma patients (pages 835–836)

      Michael K. Brawer

      Article first published online: 9 NOV 2000 | DOI: 10.1002/(SICI)1097-0142(19980901)83:5<835::AID-CNCR3>3.0.CO;2-H

      It is a true tribute to Dr. Donald F. Gleason that his grading system remains the most important predictor of success or failure in the treatment of clinically localized prostate carcinoma. Until new prognostic markers are well established, the histologic information represented by a Gleason score of 7 or higher will be useful in counseling patients about treatment.

      See also pages 971-6.

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      Cost-effectiveness of hepatic artery infusion chemotherapy (pages 837–838)

      Boris W. Kuvshinoff

      Article first published online: 9 NOV 2000 | DOI: 10.1002/(SICI)1097-0142(19980901)83:5<837::AID-CNCR4>3.0.CO;2-F

      The cost-effectiveness of hepatic artery and systemic chemotherapies within a national health care system are within the range of other currently accepted cancer treatments. Cost analysis with a fee-for-service system using prospective randomized data is needed.

      See also pages 882-8.

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      Interphase cytogenetics for studying solid tumors (pages 839–843)

      Hon Fong L. Mark

      Article first published online: 9 NOV 2000 | DOI: 10.1002/(SICI)1097-0142(19980901)83:5<839::AID-CNCR5>3.0.CO;2-D

      Interphase cytogenetics is a powerful tool for studying biomarkers in solid tumors, as discussed in the report on prostate adenocarcinoma by Henke et al. in this issue of Cancer.

      See also pages 977-88.

    4. Counterpoint

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      Staging in thyroid carcinoma (pages 844–847)

      Blake Cady

      Article first published online: 9 NOV 2000 | DOI: 10.1002/(SICI)1097-0142(19980901)83:5<844::AID-CNCR6>3.0.CO;2-I

      In this issue of Cancer a new staging system for thyroid carcinoma is proposed that resembles the TNM System currently in use. Although developing yet another staging system for thyroid carcinoma to compensate for previous deficiencies may be potentially helpful, the real need is to convince surgeons and endocrinologists to modify and adjust therapeutic aggressiveness to the risk of the tumor rather than treat every patient in exactly the same fashion. Because multiple previous staging systems have not altered current therapy guidelines, doubt is raised that this new system will be any more successful in this important attempt to individualize therapy.

      See also pages 848-50 and 1012-21.

    5. Reply to Counterpoint

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      Staging of thyroid carcinoma-reply (pages 848–850)

      Steven I. Sherman

      Article first published online: 9 NOV 2000 | DOI: 10.1002/(SICI)1097-0142(19980901)83:5<848::AID-CNCR7>3.0.CO;2-E

      See also pages 844-7 and 1012-21.

  4. Original Articles

    1. Top of page
    2. Cancer—50 Years Later
    3. Commentaries
    4. Editorials
    5. Original Articles
    6. Communications
    7. Correspondence
    1. Anatomic Site

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      Expression of P-glycoprotein, a multidrug-resistance gene product, is Induced by radiotherapy in patients with oral squamous cell carcinoma (pages 851–857)

      Irene O. L. Ng, King Y. Lam, Matthew Ng, Dora L.W. Kwong and Jonathan S. T. Sham

      Article first published online: 9 NOV 2000 | DOI: 10.1002/(SICI)1097-0142(19980901)83:5<851::AID-CNCR8>3.0.CO;2-L

      Expression of P-glycoprotein, a multidrug-resistance gene product, is induced in oral cancer cells after radiotherapy. This may explain the lower rate of response to chemotherapy among patients who have previously had radiotherapy. It may also confer multidrug resistance to the cancer cells, affecting the efficacy of subsequent or concurrent chemotherapy.

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      Micrometastasis and tumor cell microinvolvement of lymph nodes from esophageal squamous cell carcinoma : Frequency, associated tumor characteristics, and impact on prognosis (pages 858–866)

      Shoji Natsugoe, James Mueller, Hubert J. Stein, Marcus Feith, Heinz Höfler and J. Rüdiger Siewert

      Article first published online: 9 NOV 2000 | DOI: 10.1002/(SICI)1097-0142(19980901)83:5<858::AID-CNCR9>3.0.CO;2-E

      Lymph node micrometastases detected by immunohistochemistry from esophageal squamous cell carcinoma are not uncommon and have the same adverse prognostic impact as lymph node metastases detected by routine histologic methods.

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      Clonal analysis of superficial depressed-type gastric carcinoma in humans (pages 867–875)

      Masamichi Bamba, Hiroyuki Sugihara, Katsuji Okada, Tadao Bamba and Takanori Hattori

      Article first published online: 9 NOV 2000 | DOI: 10.1002/(SICI)1097-0142(19980901)83:5<867::AID-CNCR10>3.0.CO;2-T

      In this study, most of the superficial depressed-type gastric carcinomas were of monoclonal origin as demonstrated by the HUMARA assay.

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      Increased cell proliferation of the gastric mucosa in first-degree relatives of gastric carcinoma patients (pages 876–881)

      Alexander Meining, Andreas Hackelsberger, Carsten Daenecke, Manfred Stolte, Ekkehard Bayerdörffer and Thomas Ochsenkühn

      Article first published online: 9 NOV 2000 | DOI: 10.1002/(SICI)1097-0142(19980901)83:5<876::AID-CNCR11>3.0.CO;2-S

      First-degree relatives of gastric carcinoma patients have significantly increased cell proliferation of the gastric mucosa compared with controls without such a family history. These individuals may have an increased risk of developing gastric carcinoma independent of infection with Helicobacter pylori.

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      Cost-effectiveness of systemic and regional chemotherapy for the treatment of patients with unresectable colorectal liver metastases (pages 882–888)

      Isabelle Durand-Zaleski, Sally Earlam, Carol Fordy, Michael Davies and Timothy G. Allen-Mersh

      Article first published online: 9 NOV 2000 | DOI: 10.1002/(SICI)1097-0142(19980901)83:5<882::AID-CNCR12>3.0.CO;2-R

      The least expensive management of patients with colorectal liver metastases was symptom control, whereas systemic and hepatic arterial infusion chemotherapies were equally cost-effective in producing additional normal quality of survival for health care resources expended.

      See also pages 837-8.

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      Microsatellite instability and p53 mutations in sporadic right and left colon carcinoma : Different clinical and molecular implications (pages 889–895)

      Matilde E. Lleonart, Jesús García-Foncillas, Ricardo Sánchez-Prieto, Pilar Martín, Amalia Moreno, Clara Salas and Santiago Ramón y Cajal

      Article first published online: 9 NOV 2000 | DOI: 10.1002/(SICI)1097-0142(19980901)83:5<889::AID-CNCR13>3.0.CO;2-R

      Microsatellite instability in sporadic right colon carcinoma is related to tumor size and is not associated with mutations in the hMLH1 and hMSH2 DNA repair genes or in the p53 gene.

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      Infrequent somatic mutation of the adenomatous polyposis coli gene in aberrant crypt foci of human colon tissue (pages 896–900)

      Kazuhiko Otori, Motoko Konishi, Kenji Sugiyama, Takahiro Hasebe, Tadakazu Shimoda, Rei Kikuchi-Yanoshita, Kiyoshi Mukai, Shoji Fukushima, Michiko Miyaki and Hiroyasu Esumi

      Article first published online: 9 NOV 2000 | DOI: 10.1002/(SICI)1097-0142(19980901)83:5<896::AID-CNCR14>3.0.CO;2-Q

      Somatic mutations in the mutation cluster regions of the adenomatous polyposis coli gene were evaluated for human aberrant crypt foci (ACF). The mutations were found in only a limited number of adenomas in ACF.

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      Retrospective analysis of the effect of interferon therapy on the clinical outcome of patients with viral cirrhosis (pages 901–909)

      Luisa Benvegnù, Liliana Chemello, Franco Noventa, Giovanna Fattovich, Patrizia Pontisso and Alfredo Alberti

      Article first published online: 9 NOV 2000 | DOI: 10.1002/(SICI)1097-0142(19980901)83:5<901::AID-CNCR15>3.0.CO;2-Z

      These results support the hypothesis that interferon therapy improves the clinical outcome and reduces the risk of development of hepatocellular carcinoma in hepatitis C virus-related cirrhosis. These conclusions, based on retrospective data, should be confirmed prospectively.

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      Development of a new staging system for patients with recurrent laryngeal squamous cell carcinoma (pages 910–917)

      Peter D. Lacy and Jay F. Piccirillo

      Article first published online: 9 NOV 2000 | DOI: 10.1002/(SICI)1097-0142(19980901)83:5<910::AID-CNCR16>3.0.CO;2-Y

      Significant variables affecting survival for patients with laryngeal squamous cell carcinoma recurrence were combined to create a new staging system.

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      The prognostic significance of fluorodeoxyglucose positron emission tomography imaging for patients with nonsmall cell lung carcinoma (pages 918–924)

      Vinita Ahuja, R. Edward Coleman, James Herndon and Edward F. Patz Jr.

      Article first published online: 9 NOV 2000 | DOI: 10.1002/(SICI)1097-0142(19980901)83:5<918::AID-CNCR17>3.0.CO;2-Y

      The amount of fluorodeoxyglucose uptake in lung carcinoma correlates with prognosis and may be a useful marker in determining treatment options.

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      Multimodality treatment of primary lymphoepithelioma-like carcinoma of the lung (pages 925–929)

      Anthony T. C. Chan, Peter M. L. Teo, Kwok C. Lam, Wing Y. Chan, John H. S. Chow, Anthony P. C. Yim, Tony S. K. Mok, Wing H. Kwan, Thomas W. T. Leung and Philip J. Johnson

      Article first published online: 9 NOV 2000 | DOI: 10.1002/(SICI)1097-0142(19980901)83:5<925::AID-CNCR18>3.0.CO;2-X

      Primary lymphoepithelioma-like carcinoma of the lung is a chemosensitive tumor. Multimodality treatment is recommended.

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      Intracellular accumulation of thallium as a marker of cisplatin cytotoxicity in nonsmall cell lung carcinoma : An application of inductively coupled plasma mass spectrometry (pages 930–935)

      Taro Hanada, Hiroshi Isobe, Takeshi Saito, Shigeaki Ogura, Hironori Takekawa, Kohichi Yamazaki, Yoshio Tokuchi and Yoshikazu Kawakami

      Article first published online: 9 NOV 2000 | DOI: 10.1002/(SICI)1097-0142(19980901)83:5<930::AID-CNCR19>3.0.CO;2-W

      Cellular thallium accumulation determined by inductively coupled plasma mass spectrometry may represent cisplatin cytotoxicity in nonsmall cell lung carcinoma cell lines.

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      Multimodality treatment of 128 patients with locally advanced breast carcinoma in the era of mammography screening using standard polychemotherapy with 5-fluorouracil, epirubicin, and cyclophosphamide : Prognostic and therapeutic implications (pages 936–947)

      Ylva A. Karlsson, Per O. Malmström, Thomas Hatschek, Tommy G. Fornander, Martin Söderberg, Nils-Olof Bengtsson, Tomas E. Jansson, Sara M. Sjöberg and Jonas C. Bergh

      Article first published online: 9 NOV 2000 | DOI: 10.1002/(SICI)1097-0142(19980901)83:5<936::AID-CNCR20>3.0.CO;2-V

      This article describes 128 patients with locally advanced breast carcinoma enrolled during the time period when 6 of 8 departments participating in this therapy program in Sweden had population-based screening programs. The results with multimodal therapy-including polychemotherapy with 5-fluorouracil, epirubicin, and cyclophosphamide-indicate outcome data similar to that for unscreened populations.

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      Prediction of axillary lymph node involvement of women with invasive breast carcinoma : A multivariate analysis (pages 948–955)

      Ivo A. Olivotto, Jeremy S. H. Jackson, Donna Mates, Sandra Andersen, Warren Davidson, Cicely J. Bryce and Joseph Ragaz

      Article first published online: 9 NOV 2000 | DOI: 10.1002/(SICI)1097-0142(19980901)83:5<948::AID-CNCR21>3.0.CO;2-U

      A multivariate analysis of 12 clinical and pathologic variables in a large, current, population-based cohort of 4660 women with invasive breast carcinoma produced a six-variable model that predicted a high (≥90%) or low (≤10%) risk of axillary lymph node involvement for >30% of study subjects. A clinically useful, three-variable model employing tumor size, clinical tumor and lymph node palpability, and the presence or absence of lymphatic or vascular invasion produced similar levels of prediction accuracy.

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      Prognostic impact of morphometric nuclear grade of endometrial carcinoma (pages 956–964)

      Helga B. Salvesen, Ole Erik Iversen and Lars A. Akslen

      Article first published online: 9 NOV 2000 | DOI: 10.1002/(SICI)1097-0142(19980901)83:5<956::AID-CNCR22>3.0.CO;2-T

      Morphometrically determined nuclear size has an independent prognostic impact in patients with endometrial carcinoma.

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      Histologic characterization of rat ovarian carcinoma induced by intraovarian insertion of a 7,12-dimethylbenz[a]anthracene-coated suture : Common epithelial tumors of the ovary in rats? (pages 965–970)

      Takashi Nishida, Toru Sugiyama, Akio Kataoka, Kimio Ushijima and Michiaki Yakushiji

      Article first published online: 9 NOV 2000 | DOI: 10.1002/(SICI)1097-0142(19980901)83:5<965::AID-CNCR23>3.0.CO;2-S

      The histology of rat ovarian carcinomas induced by intraovarian insertion of 7,12-dimethylbenz[a]anthracene-coated silk simulates that of müllerian derivatives.

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      A gleason score of 7 predicts a worse outcome for prostate carcinoma patients treated with radiotherapy (pages 971–976)

      Garth A. Green, Alexandra L. Hanlon, Tahseen Al-Saleem and Gerald E. Hanks

      Article first published online: 9 NOV 2000 | DOI: 10.1002/(SICI)1097-0142(19980901)83:5<971::AID-CNCR24>3.0.CO;2-R

      In a multivariate analysis, patients with a Gleason score of 7 adenocarcinoma of the prostate who received radiotherapy had a poorer survival without biochemical failure (bNED) than those with a Gleason score of 5-6, even after controlling for other strong prognostic factors, including pretreatment prostate specific antigen levels. A Gleason score of 7 is not moderately differentiated; thus, these patients should not be grouped together with those who have a Gleason score of 5-6. See also pages 835-6.

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      Interphase cytogenetic study of preoperative core biopsies for the prediction of early serum prostate specific antigen recurrence after radical prostatectomy of clinically localized prostate carcinoma (pages 977–988)

      R.-Peter Henke, Peter Hammerer, Marcus Graefen, Andreas Erbersdobler, Matthias Neumann, Jürgen Berger and Hartwig Huland

      Article first published online: 9 NOV 2000 | DOI: 10.1002/(SICI)1097-0142(19980901)83:5<977::AID-CNCR25>3.0.CO;2-R

      Interphase cytogenetics with chromosome enumeration probes, used in the evaluation of preoperative core biopsies from patients with clinically localized prostate carcinoma, predict recurrence of elevated serum concentrations of prostate specific antigen after radical retropubic prostatectomy.

      See also pages 839-43.

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      Ten-year disease free survival after transperineal sonography-guided iodine-125 brachytherapy with or without 45-gray external beam irradiation in the treatment of patients with clinically localized, low to high gleason grade prostate carcinoma (pages 989–1001)

      Haakon Ragde, Abdel-Aziz A. Elgamal, Peter B. Snow, Jeff Brandt, Alfred A. Bartolucci, Brad S. Nadir and Leroy J. Korb

      Article first published online: 9 NOV 2000 | DOI: 10.1002/(SICI)1097-0142(19980901)83:5<989::AID-CNCR26>3.0.CO;2-Q

      Percutaneous sonography-guided prostate brachytherapy is a valid therapy for patients with low to high Gleason grade, clinically organ-confined prostate carcinoma. Observed 10-year follow-up of 152 consecutively treated patients documents prostate specific antigen values comparable to those reported after radical prostatectomy and external beam irradiation.

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      Prognostic risk factors that identify patients with clinical stage I nonseminomatous germ cell tumors at low risk and high risk for metastasis (pages 1002–1011)

      Axel Heidenreich, Isabell A. Sesterhenn, F. Kash Mostofi and Judd W. Moul

      Article first published online: 9 NOV 2000 | DOI: 10.1002/(SICI)1097-0142(19980901)83:5<1002::AID-CNCR27>3.0.CO;2-A

      This retrospective study evaluated prognostic risk factors for patients with low stage nonseminomatous testicular germ cell tumors. These factors included the percentage of each histologic cell type; the presence or absence of vascular invasion; and the immunohistochemical expression of MIB-1, p53, bcl-2, cathepsin D, and E-cadherin. Multivariate analysis identified, with more than 90% accuracy, the percentage of embryonal carcinoma and vascular invasion as independent prognosticators that identified patients at high and low risk for occult retroperitoneal disease.

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      Prospective multicenter study of thyroid carcinoma treatment : Initial analysis of staging and outcome (pages 1012–1021)

      Steven I. Sherman, James D. Brierley, Matthew Sperling, Kenneth B. Ain, S. Thomas Bigos, David S. Cooper, Bryan R. Haugen, Mona Ho, Irwin Klein, Paul W. Ladenson, Jacob Robbins, Douglas S. Ross, Bonny Specker, Terry Taylor and Harry R. Maxon III

      Article first published online: 9 NOV 2000 | DOI: 10.1002/(SICI)1097-0142(19980901)83:5<1012::AID-CNCR28>3.0.CO;2-9

      A novel prognostic staging classification encompassing all forms of thyroid carcinoma was created for a prospective multicenter registry. This staging classification provides a prospectively validated scheme for predicting short term prognosis comparable if not superior to other available classifications for thyroid carcinoma.

      See also pages 844-7 and 848-50.

    22. General Topic

      Antiemetic Therapy
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      A study evaluating the efficacy and tolerability of tropisetron in combination with dexamethasone in the prevention of delayed platinum-induced nausea and emesis (pages 1022–1032)

      Bengt G. Sorbe, Anne-Marie Berglind, Håkan Andersson, Karin Boman, Thomas Högberg, Monica Hallgren and Margareta Schmidt

      Article first published online: 9 NOV 2000 | DOI: 10.1002/(SICI)1097-0142(19980901)83:5<1022::AID-CNCR29>3.0.CO;2-8

      Tropisetron, a 5-HT3 receptor antagonist, was found to add to the effect of dexamethasone in the prevention of delayed nausea, but delayed emesis was not affected.

  5. Communications

    1. Top of page
    2. Cancer—50 Years Later
    3. Commentaries
    4. Editorials
    5. Original Articles
    6. Communications
    7. Correspondence
    1. General Topic

      The American College of Surgeons Commission on Cancer and the American Cancer Society
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      The national cancer data base report on cancer of the vagina (pages 1033–1040)

      William T. Creasman, Jerri Linn Phillips and Herman R. Menck

      Article first published online: 9 NOV 2000 | DOI: 10.1002/(SICI)1097-0142(19980901)83:5<1033::AID-CNCR30>3.0.CO;2-6

      Demographic characteristics, treatment, and survival outcome of 4885 patients with cancer of the vagina diagnosed between 1985 and 1994 are described.

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      The national cancer data base report on hodgkin's disease for 1985-1989 and 1990-1994 (pages 1041–1047)

      B.J. Kennedy, Amy M. Fremgen and Herman R. Menck

      Article first published online: 9 NOV 2000 | DOI: 10.1002/(SICI)1097-0142(19980901)83:5<1041::AID-CNCR31>3.0.CO;2-5

      The National Cancer Data Base provided data submitted voluntarily by hospital cancer registries throughout the United States during the period 1985-1994, reflecting the status of Hodgkin's disease management of 35,033 patients. For 1994, the reported cases represented 60.6% of the estimated occurrence of Hodgkin's disease for that year. National progress has been made in the use of staging, improved therapeutics, and greater long term survival. Older patients have poorer prognoses than younger patients for all stages.

  6. Correspondence

    1. Top of page
    2. Cancer—50 Years Later
    3. Commentaries
    4. Editorials
    5. Original Articles
    6. Communications
    7. Correspondence
    1. You have free access to this content
      Radiation-induced sarcoma-50 years later (page 1048)

      Hans-Peter Beck-Bornholdt and Horst Jung

      Article first published online: 9 NOV 2000 | DOI: 10.1002/(SICI)1097-0142(19980901)83:5<1048::AID-CNCR32>3.0.CO;2-5

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      Author reply (pages 1048–1049)

      William G. Cahan

      Article first published online: 9 NOV 2000 | DOI: 10.1002/(SICI)1097-0142(19980901)83:5<1048::AID-CNCR33>3.0.CO;2-5

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      Resection of hepatic and pulmonary metastases in patients with colorectal carcinoma (pages 1049–1050)

      Lorenzo Spaggiari, Dominique Grunenwald and Jean François Regnard

      Article first published online: 9 NOV 2000 | DOI: 10.1002/(SICI)1097-0142(19980901)83:5<1049::AID-CNCR34>3.0.CO;2-5

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      Author reply (pages 1050–1051)

      Satoshi Ambiru, Masaru Miyazaki and Nobuyuki Nakajima

      Article first published online: 9 NOV 2000 | DOI: 10.1002/(SICI)1097-0142(19980901)83:5<1050::AID-CNCR35>3.0.CO;2-4

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      Undifferentiated carcinoma with osteoclast-like giant cells of the pancreas and periampullary region (page 1051)

      Kim Deckard-Janatpour, Raymond L. Teplitz, Byung Hee Min, Boris H. Ruebner and Paul H. Gumerlock

      Article first published online: 9 NOV 2000 | DOI: 10.1002/(SICI)1097-0142(19980901)83:5<1051::AID-CNCR36>3.0.CO;2-4

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      Author reply (pages 1051–1052)

      Kyle H. Molberg, Ruby Delgado, Jorge Albores-Saavedra and Clara Heffess

      Article first published online: 9 NOV 2000 | DOI: 10.1002/(SICI)1097-0142(19980901)83:5<1051::AID-CNCR37>3.0.CO;2-4

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      Expression of cytokeratin 20 in urinary cytology of patients with bladder carcinoma (pages 1052–1053)

      Jennifer Southgate, Dawn Lobban and Patricia Harnden

      Article first published online: 9 NOV 2000 | DOI: 10.1002/(SICI)1097-0142(19980901)83:5<1052::AID-CNCR38>3.0.CO;2-4

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      Author reply (pages 1053–1054)

      Ami Klein, Ruth Zemer, Ronen Klaper, Israel Nissenkorn and Victor Buchumensky

      Article first published online: 9 NOV 2000 | DOI: 10.1002/(SICI)1097-0142(19980901)83:5<1053::AID-CNCR39>3.0.CO;2-4

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      Hand-foot syndrome following prolonged infusion of high doses of vinorelbine (page 1054)

      Fred Rosner

      Article first published online: 9 NOV 2000 | DOI: 10.1002/(SICI)1097-0142(19980901)83:5<1054::AID-CNCR40>3.0.CO;2-3

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      Author reply (pages 1054–1055)

      Paulo M. Hoff, Vincente Valero, Nuhad Ibrahim, Jie Willey and Gabriel N. Hortobagyi

      Article first published online: 9 NOV 2000 | DOI: 10.1002/(SICI)1097-0142(19980901)83:5<1054::AID-CNCR41>3.0.CO;2-3

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      Cancer among spouses : Review of 195 couples (page 1055)

      Gary D. Friedman and Charles P. Quesenberry Jr.

      Article first published online: 9 NOV 2000 | DOI: 10.1002/(SICI)1097-0142(19980901)83:5<1055::AID-CNCR42>3.0.CO;2-3

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      Author reply (page 1055)

      Natalio Walach, Ilya Novikov and Baruch Modan

      Article first published online: 9 NOV 2000 | DOI: 10.1002/(SICI)1097-0142(19980901)83:5<1055::AID-CNCR43>3.0.CO;2-3

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      Intensified therapy for infants with acute lymphoblastic leukemia : Results from the Dana-Farber Cancer Institute Consortium (pages 1055–1057)

      Tomasz Szczepański, Marja J. Pongers-Willemse, Karel Hählen and Jacques J. M. van Dongen

      Article first published online: 9 NOV 2000 | DOI: 10.1002/(SICI)1097-0142(19980901)83:5<1055::AID-CNCR44>3.0.CO;2-3

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      Report of a panel on the relationship between public exposure to pesticides and cancer (pages 1057–1058)

      Philip J. Landrigan and Lynn R. Goldman

      Article first published online: 9 NOV 2000 | DOI: 10.1002/(SICI)1097-0142(19980901)83:5<1057::AID-CNCR45>3.0.CO;2-3

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      Author reply (pages 1058–1060)

      Leonard Ritter, Clark Heath Jr., Elizabeth Kaegi, Howard Morrison and Susan Sieber

      Article first published online: 9 NOV 2000 | DOI: 10.1002/(SICI)1097-0142(19980901)83:5<1058::AID-CNCR46>3.0.CO;2-3

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