• Please log in or register to access this feature.

Research Article

You have full text access to this OnlineOpen article

Platinum organ toxicity and possible prevention in patients with testicular cancer

  1. Jörg Thomas Hartmann*,
  2. Christian Kollmannsberger,
  3. Lothar Kanz,
  4. Carsten Bokemeyer

Article first published online: 19 NOV 1999

DOI: 10.1002/(SICI)1097-0215(19991210)83:6<866::AID-IJC34>3.0.CO;2-9

Issue

International Journal of Cancer

International Journal of Cancer

Volume 83, Issue 6, pages 866–869, 10 December 1999

Additional Information

How to Cite

Hartmann, J. T., Kollmannsberger, C., Kanz, L. and Bokemeyer, C. (1999), Platinum organ toxicity and possible prevention in patients with testicular cancer. Int. J. Cancer, 83: 866–869. doi: 10.1002/(SICI)1097-0215(19991210)83:6<866::AID-IJC34>3.0.CO;2-9

Author Information

  1. Department of Hematology/Oncology/Immunology, UKT-Medical Center II, Eberhard-Karls-University, Tuebingen, Germany

*Department of Hematology/Oncology/Immunology, UKT-Medical Center II, Eberhard-Karls-University, Otfried-Mueller-Str. 10, D-72076 Tuebingen, Germany. Fax: +49 (0)7071 29 3675.

Publication History

  1. Issue published online: 19 NOV 1999
  2. Article first published online: 19 NOV 1999

SEARCH

SEARCH BY CITATION

ARTICLE TOOLS

View Full Article (HTML) Get PDF (83K)

REFERENCES

  • Berger, C.C., Bokemeyer, C., Schuppert, F. and Schmoll, H.J., Endocrinological late effects after chemotherapy for testicular cancer. Brit. J. Cancer, 73, 1108-1114 (1996). Medline
  • Bissett, D., Kunkeler, L., Zwanenburg, L., Paul, J., Gray, C., Swan, I.R., Kerr, D.J. and Kaye, S.B., Long-term sequelae of treatment for testicular germ cell tumours. Brit. J. Cancer, 62, 655-659 (1990). Medline
  • Bokemeyer, C., Berger, C.C., Hartmann, J.T., Kollmannsberger, C., Schmoll, H.J., Kuczyk, M.A. and Kanz, L., Analysis of risk factors for cisplatin-induced ototoxicity in patients with testicular cancer. Brit. J. Cancer, 77, 1355-1362 (1998). Medline
  • Bokemeyer, C., Berger, C.C., Kuczyk, M.A. and Schmoll, H.J., Evaluation of long-term toxicity after chemotherapy for testicular cancer. J. clin. Oncol., 14, 2923-2932 (1996). Medline
  • Bokemeyer, C., Hartmann, J.T., Fels, L., Knop, S., Brugger, W., Stolte, H. and Anz, L., Amifostine protects against early cisplatin-induced renal damage and enhances CD34+-cell numbers for PBSC-collection. Proc. Amer. Soc. clin. Oncol., 16, 47a (1997). Abstract nr. 166.
  • Bokemeyer, C. and 15 others, A phase I/II study of a stepwise dose-escalated regimen of cisplatin, etoposide and ifosfamide plus granulocyte-macrophage colony-stimulating factor (GM-CSF) in patients with advanced germ cell tumours. Europ. J. Cancer, 29A, 2225-2231 (1993).
  • Coleman, M.P., Esteve, J., Damiecki, P., Arslan, A. and Renard, H., Trends in cancer incidence and mortality, IARC Scientific Publication, IARC, Lyon, France, 12, 1-806 (1993).
  • Daugaard, G., Rossing, N. and Rorth, M., Effects of cisplatin on different measures of glomerular function in the human kidney with special emphasis on high-dose. Cancer Chemother. Pharmacol., 21, 163-167 (1988). Medline
  • Dunn, T.A., Schmoll, H.J., Grunwald, V., Bokemeyer, C. and Casper, J., Amifostine does not alter the antitumor activity of cisplatin in a pre-clinical model of testicular cancer. Anticancer Drugs, 7, 795-799 (1996). Medline
  • Fjeldborg, P., Sorensen, J. and Helkjaer, P.E., The long-term effect of cisplatin on renal function. Cancer, 58, 2214-2217 (1986). Medline
    Direct Link:
  • Groth, S., Nielsen, H., Sorensen, J.B., Christensen, A.B., Pedersen, A.G. and Rorth, M., Acute and long-term nephrotoxicity of cis-platinum in man. Cancer Chemother. Pharmacol., 17, 191-196 (1986). Medline
  • Hamilton, C.R., Bliss, J.M. and Horwich, A., The late effects of cis-platinum on renal function. Europ. J. Cancer clin. Oncol., 25, 185-189 (1989). Medline
  • Hansen, S.W., Groth, S., Daugaard, G., Rossing, N. and Rorth, M., Long-term effects on renal function and blood pressure of treatment with cisplatin, vinblastine, and bleomycin in patients with germ cell cancer. J. clin. Oncol., 6, 1728-1731 (1988). Medline
  • Hansen, S.W., Helweg Larsen, S. and Trojaborg, W., Long-term neurotoxicity in patients treated with cisplatin, vinblastine, and bleomycin for metastatic germ cell cancer. J. clin. Oncol., 7, 1457-1461 (1989). Medline
  • Hansen, S.W. and Olsen, N., Raynaud's phenomenon in patients treated with cisplatin, vinblastine, and bleomycin for germ cell cancer: Measurement of vasoconstrictor response to cold. J. clin. Oncol., 7, 940-942 (1989). Medline
  • Hartmann, J.T., Albrecht, C., Schmoll, H.J., Kollmannsberger, C. and Bokemeyer, C., Long-term effects on sexual functioning and fertility after treatment for testicular cancer. Brit. J. Cancer, 80, 801-807 (1999a). Medline
  • Hartmann, J.T., Kanz, L. and Bokemeyer, C., Diagnosis and treatment of patients with testicular cancer. Drugs, 58, 257-281 (1999b). Medline
  • Hartmann, J.T., von Wangerow, A., Knop, S., Fels, L., Brugger, W., Stolte, H., Kanz, L. and Bokemeyer, C., A randomized trial comparing the toxicity of high dose chemotherapy with carboplatin, etoposide and ifosfamide plus PBSC transplantation (HD-VIC) with or without amifostine in patients with solid tumors. Proc. Amer. Soc. clin. Oncol., 18, 587a (1999c). Abstract nr. 2266.
  • Hernes, E.H., Harstad, K. and Fosså, S.D., Changing incidence and delay of testicular cancer in southern Norway (1981-1992). Europ. Urol., 30, 349-357 (1996).
  • Kemp, G., Rose, P., Lurain, J., Berman, M., Manetta, A., Roullet, B., Homesley, H., Belpomme, D. and Glick, J., Amifostine pretreatment for protection against cyclophosphamide-induced and cisplatin-induced toxicities: Results of a randomized control trial in patients with advanced ovarian cancer. J. clin. Oncol., 14, 2101-2112 (1996). Medline
  • Macleod, P.M., Tyrell, C.J. and Keeling, D.H., The effect of cisplatin on renal function in patients with testicular tumours. Clin. Radiol., 39, 190-192 (1988). Medline
  • Moul, J.W., Robertson, J.E., George, S.L., Paulson, D.F. and Walther, P.J., Complications of therapy for testicular cancer. J. Urol., 142, 1491-1496 (1989). Medline
  • Nichols, C.R., Testicular cancer. Curr. Probl. Cancer, 22, 187-274 (1998). Medline
  • Osanto, S., Bukman, A., van Hoek, F., Sterk, P.J., de Llaat, J.A. and Hermans, J., Long-term effects of chemotherapy in patients with testicular cancer. J. clin. Oncol., 10, 574-579 (1992). Medline
  • Reddel, R.R., Kefford, R.F., Grant, J.M., Coates, A.S., Fox, R.M. and Tattersall, M.H., Ototoxicity in patients receiving cisplatin: Importance of dose and method of drug administration. Cancer Treat. Rep., 66, 19-23 (1982). Medline
  • Roth, B.J., Einhorn, L.H. and Greist, A., Long-term complications of cisplatin-based chemotherapy for testis cancer. Semin. Oncol., 15, 345-350 (1988). Medline
  • Schuchter, L.M., Meropol, N. and Glick, J.H., Radiation and chemotherapy protectors. In: V.T.De Vita, S.Hellmann and S.A.Rosenberg (eds.), Cancer principles and practice of oncology (5th ed.), pp. 387-392, Lippincott-Raven, Philadelphia (1997).
  • Siegert, W., Beyer, J., Strohscheer, I., Baurmann, H., Oettle, H., Zingsem, J., Zimmermann, R., Bokemeyer, C., Schmoll, H.J. and Hühn, D., High-dose treatment with carboplatin, etoposide, and ifosfamide followed by autologous stem-cell transplantation in relapsed or refractory germ cell cancer: A phase I/II study. The German Testicular Cancer Cooperative Study Group. J. clin. Oncol., 12, 1223-1231 (1994). Medline
  • Teutsch, C., Lipton, A. and Harvey, H.A., Raynaud's phenomenon as a side effect of chemotherapy with vinblastine and bleomycin for testicular carcinoma. Cancer Treat. Rep., 61, 925-926 (1977). Medline
  • Thompson, S.W., Davis, L.E., Kornfeld, M., Hilgers, R.D. and Standefer, J.C., Cisplatin neuropathy. Clinical, electrophysiologic, morphologic, and toxicologic studies. Cancer, 54, 1269-1275 (1984). Medline
    Direct Link:
  • Treskes, M. and van der Vijgh, W.J., WR2721 as a modulator of cisplatin- and carboplatin-induced side effects in comparison with other chemoprotective agents: A molecular approach. Cancer Chemother. Pharmacol., 33, 93-106 (1993). Medline
  • van der Hulst, R.J., Dreschler, W.A. and Urbanus, N.A., High frequency audiometry in prospective clinical research of ototoxicity due to platinum derivatives. Ann. Otol. Rhinol. Laryngol., 97, 133-137 (1988). Medline
  • Vogelzang, N.J., Bosl, G.J., Johnson, K. and Kennedy, B.J., Raynaud's phenomenon: A common toxicity after combination chemotherapy for testicular cancer. Ann. Intern. Med., 95, 288-292 (1981). Medline
  • Wagstaff, A.J., Ward, A., Benfield, P. and Heel, R.C., Carboplatin. A preliminary review of its pharmacodynamic and pharmacokinetic properties and therapeutic efficacy in the treatment of cancer. Drugs, 37, 162-190 (1989). Medline
  • Yagoda, A., Mukherji, B., Young, C., Etcubanas, E., Lamonte, C., Smith, J.R., Tan, C.T. and Krakoff, I.H., Bleomycin, an antitumor antibiotic. Clinical experience in 274 patients. Ann. Intern. Med., 77, 861-870 (1972). Medline
View Full Article (HTML) Get PDF (83K)