Research Article

Modelling cure rates using the Gompertz model with covariate information

  1. Peter W. Gieser1,*,
  2. Myron N. Chang1,
  3. P. V. Rao1,
  4. Jonathan J. Shuster1,
  5. Jeanette Pullen2

Article first published online: 4 DEC 1998

DOI: 10.1002/(SICI)1097-0258(19980430)17:8<831::AID-SIM790>3.0.CO;2-G

Issue

Statistics in Medicine

Statistics in Medicine

Volume 17, Issue 8, pages 831–839, 30 April 1998

Additional Information

How to Cite

Gieser, P. W., Chang, M. N., Rao, P. V., Shuster, J. J. and Pullen, J. (1998), Modelling cure rates using the Gompertz model with covariate information. Statist. Med., 17: 831–839. doi: 10.1002/(SICI)1097-0258(19980430)17:8<831::AID-SIM790>3.0.CO;2-G

Author Information

  1. 1

    Pediatric Oncology Group Statistical Office, 104 N. Main St., Gainesville, FL 32601-3330, U.S.A.

  2. 2

    University of Mississippi Medical Center, 2500 N. State St., Jackson, MS 39216, U.S.A.

*Pediatric Oncology Group Statistical Office, 104 N. Main St., Gainesville, FL 32601-3330, U.S.A.

Publication History

  1. Issue published online: 4 DEC 1998
  2. Article first published online: 4 DEC 1998
  3. Manuscript Revised: APR 1997
  4. Manuscript Received: APR 1996

Funded by

  • National Cancer Institute. Grant Number: CA 29139

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Abstract

We extend the modified Gompertz hazard function, first used by Cantor and Shuster for estimation of cure rates from pediatric clinical trials, by including covariate effects. The extended model provides a convenient method for estimation of the cure rate as a function of treatments and covariates. © 1998 John Wiley & Sons, Ltd.

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