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Research Article
Extracting summary statistics to perform meta-analyses of the published literature for survival endpoints
Article first published online: 5 JAN 1999
DOI: 10.1002/(SICI)1097-0258(19981230)17:24<2815::AID-SIM110>3.0.CO;2-8
Copyright © 1998 John Wiley & Sons, Ltd.
Issue
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Statistics in Medicine
Special Issue: Papers from the International Meetings of the International Society for Clinical Biostatistics
Volume 17, Issue 24, pages 2815–2834, 30 December 1998
Additional Information
How to Cite
Parmar, M. K. B., Torri, V. and Stewart, L. (1998), Extracting summary statistics to perform meta-analyses of the published literature for survival endpoints. Statist. Med., 17: 2815–2834. doi: 10.1002/(SICI)1097-0258(19981230)17:24<2815::AID-SIM110>3.0.CO;2-8
Publication History
- Issue published online: 5 JAN 1999
- Article first published online: 5 JAN 1999
- Abstract
- References
- Cited By
Abstract
Meta-analyses aim to provide a full and comprehensive summary of related studies which have addressed a similar question. When the studies involve time to event (survival-type) data the most appropriate statistics to use are the log hazard ratio and its variance. However, these are not always explicitly presented for each study. In this paper a number of methods of extracting estimates of these statistics in a variety of situations are presented. Use of these methods should improve the efficiency and reliability of meta-analyses of the published literature with survival-type endpoints. © 1998 John Wiley & Sons, Ltd.