Lymphoepithelial cyst (lEC) of the pancreas: Cytomorphology and differential diagnosis on fine-needle aspiration (FNA)
Article first published online: 18 MAY 1999
Copyright © 1999 Wiley-Liss, Inc.
Volume 20, Issue 6, pages 371–374, June 1999
How to Cite
Mandavilli, S. R., Port, J. and Ali, S. Z. (1999), Lymphoepithelial cyst (lEC) of the pancreas: Cytomorphology and differential diagnosis on fine-needle aspiration (FNA). Diagn. Cytopathol., 20: 371–374. doi: 10.1002/(SICI)1097-0339(199906)20:6<371::AID-DC8>3.0.CO;2-S
- Issue published online: 18 MAY 1999
- Article first published online: 18 MAY 1999
- Manuscript Accepted: 2 SEP 1998
- Manuscript Received: 5 JUN 1998
- lymphoepithelial cyst;
- fine-needle aspiration;
Lymphoepithelial cyst (LEC) of the pancreas is an extremely rare benign entity. We describe the cytopathologic findings of such a lesion in a 49-yr-old woman who was examined for epigastric pain. A trans-esophageal ultrasound-guided fine-needle aspiration of a pancreatic mass disclosed an intimate mixture of squamous epithelial cells and small, mature lymphocytes in a background of keratinaceous debris, anucleate squames, and multinucleated histiocytes. On histopathologic examination, a subsequent resection showed a multiloculated cystic lesion with a stratified squamous epithelial lining surrounded by well-formed lymphoid tissue, suggestive of LEC. The differential diagnosis includes other pancreatic pseudocysts, dermoid cyst, mucinous cystic neoplasms, adenosquamous carcinoma, and metastatic squamous cell carcinoma. Diagn. Cytopathol. 1999;20:371–374. © 1999 Wiley-Liss, Inc.