Cyst Fluid Cytology and Chemical Features in a Case of Lymphoepithelial Cyst of the Pancreas: A Rare and Difficult Preoperative Diagnosis
Article first published online: 19 OCT 1999
Copyright © 1999 Wiley-Liss, Inc.
Volume 21, Issue 5, pages 328–330, November 1999
How to Cite
Centeno, B. A., Stockwell, J. W. and Lewandrowski, K. B. (1999), Cyst Fluid Cytology and Chemical Features in a Case of Lymphoepithelial Cyst of the Pancreas: A Rare and Difficult Preoperative Diagnosis. Diagn. Cytopathol., 21: 328–330. doi: 10.1002/(SICI)1097-0339(199911)21:5<328::AID-DC6>3.0.CO;2-J
- Issue published online: 19 OCT 1999
- Article first published online: 19 OCT 1999
- Manuscript Accepted: 22 APR 1999
- Manuscript Received: 8 MAR 1999
- lymphoepithelial cyst;
- cyst fluid analysis
Most pancreatic cysts (90%) are inflammatory pseudocysts. Approximately 10% of pancreatic cysts are neoplasms, including serous cystadenomas, and mucinous tumors, some of which are malignant. Analysis of pancreatic cyst fluid obtained by percutaneous or endoscopic fine-needle aspiration is increasingly being used for the preoperative diagnosis of pancreatic or peripancreatic cysts. However, cyst fluid chemical and cytologic features in less common types of pancreatic cysts have not been reported. Lymphoepithelial cyst of the pancreas is exceedingly rare, and only occasional individual reports have described cyst fluid findings. We report on a case of lymphoepithelial cyst of the pancreas developing in a middle-aged man. Cyst fluid aspirated under radiological guidance showed elevated levels of carcinoembryonic antigen (CEA), CA19-9, CA 125, and amylase, and a viscosity greater than that of serum. A cell block preparation of a fine-needle aspiration showed tissue fragments with a keratinized squamous lining and a lymphocytic infiltrate in the wall, and abundant background keratinous debris. The cytologic and biochemical findings in this case exhibit similarities to the findings reported in other reports, and may represent a recognizable pattern on cyst fluid analysis. Diagn. Cytopathol. 1999;21:328–330. © 1999 Wiley-Liss, Inc.