Squamous cell carcinoma of the tongue in young patients: A matched-pair analysis
Article first published online: 7 DEC 1998
Copyright © 1998 John Wiley & Sons, Inc.
Head & Neck
Volume 20, Issue 5, pages 363–368, August 1998
How to Cite
Friedlander, P. L., Schantz, S. P., Shaha, A. R., Yu, G. and Shah, J. P. (1998), Squamous cell carcinoma of the tongue in young patients: A matched-pair analysis. Head Neck, 20: 363–368. doi: 10.1002/(SICI)1097-0347(199808)20:5<363::AID-HED1>3.0.CO;2-W
- Issue published online: 7 DEC 1998
- Article first published online: 7 DEC 1998
- Manuscript Accepted: 10 SEP 1997
- Manuscript Received: 15 JAN 1997
- tongue cancer;
- young patients;
Tongue cancer is seen with increasing frequency in young individuals. There is controversy concerning the clinical course and outcome for oral tongue cancer in young patients.
A retrospective review of 36 patients under 40 years of age with squamous cell carcinoma of the tongue was performed. These patients were matched to an older population. The 5-year disease-free survival; rates of local, regional, and distant failure; and rate of second primary tumor were determined for both populations.
The 5-year disease-free survival for the young patients was 62% versus 69% in the older population (p = .30). Ten of 36 (28%) of younger patients recurred locally versus five of 36 (14%) of the older patients (p = .11). Nine of 36 (25%) younger patients recurred regionally in the younger group versus six of 36 (17%) patients in the older group (p = .25). Sixteen of 36 (44%) of the younger patients had locoregional failure versus eight of 36 (22%) of the older patients (p < .05). The rates of metastatic disease and second primary lesions were similar in both populations.
In this series, younger patients with squamous cell carcinoma of the oral tongue had a higher rate of locoregional recurrence rate than did older patients. This did not translate into a survival difference. © 1998 John Wiley & Sons, Inc. Head Neck 20: 363–368, 1998.