A prospective study on quality of life of laryngeal cancer patients treated with radiotherapy
Article first published online: 23 APR 1999
Copyright © 1999 John Wiley & Sons, Inc.
Head & Neck
Volume 21, Issue 4, pages 291–296, July 1999
How to Cite
de Graeff, A., de Leeuw, R. J., Ros, W. J. G., Hordijk, G.-J., Battermann, J. J., Blijham, G. H. and Winnubst, J. A. M. (1999), A prospective study on quality of life of laryngeal cancer patients treated with radiotherapy. Head Neck, 21: 291–296. doi: 10.1002/(SICI)1097-0347(199907)21:4<291::AID-HED1>3.0.CO;2-B
- Issue published online: 23 APR 1999
- Article first published online: 23 APR 1999
- Manuscript Accepted: 30 JUL 1998
- The Netherlands Society for Scientific Research (NWO)
- laryngeal cancer;
- quality of life
The aim of this study was to describe prospectively quality of life and mood before and after radiotherapy for laryngeal cancer.
Sixty-five patients with Tis-T3 laryngeal cancer treated with radiotherapy completed the European Organization for Research and Treatment of Cancer (EORTC) Core Questionnaire, the EORTC Head and Neck Cancer module, and the Center for Epidemiologic Studies Depression Scale before treatment and 6 and 12 months later.
There was a significant but temporary deterioration of physical functioning, fatigue and most head and neck symptoms. Speech was the only symptom which improved. Patients with T2 tumors had significantly worse physical symptoms compared with patients with T1 tumors. There was a high level of depressive symptomatology at baseline, followed by an improvement after treatment.
After radiotherapy for laryngeal cancer, a temporary deterioration of physical functioning and symptoms occurs, mostly caused by side effects of treatment. Despite physical deterioration, there is an improvement of emotional functioning and mood after treatment, probably as a result of psychological adaptation and coping processes. © 1999 John Wiley & Sons, Inc. Head Neck 21: 291–296, 1999.