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Short Report
Macrophage apoptosis in muscle tissue in experimental autoimmune myasthenia gravis
Article first published online: 7 DEC 1998
DOI: 10.1002/(SICI)1097-4598(199808)21:8<1071::AID-MUS13>3.0.CO;2-X
Copyright © 1998 John Wiley & Sons, Inc.
1097-4598/asset/cover.gif?v=1&s=939b0f38e4fb160e847df620ffcf95574c28aa96 "Muscle & Nerve")
Additional Information
How to Cite
Shi, F.-D., Bai, X.-F., Li, H.-L. and Link, H. (1998), Macrophage apoptosis in muscle tissue in experimental autoimmune myasthenia gravis. Muscle & Nerve, 21: 1071–1074. doi: 10.1002/(SICI)1097-4598(199808)21:8<1071::AID-MUS13>3.0.CO;2-X
Publication History
- Issue published online: 7 DEC 1998
- Article first published online: 7 DEC 1998
- Manuscript Accepted: 10 NOV 1997
- Abstract
- References
- Cited By
Keywords:
- experimental autoimmune myasthenia gravis;
- macrophage;
- apoptosis;
- in situ tailing;
- immunocytochemistry
Abstract
Combining in situ tailing and immunocytochemical staining, we demonstrated that the infiltrating macrophages in muscle tissue sections during early phase of experimental autoimmune myasthenia gravis (EAMG) in Lewis rats were eliminated by apoptosis at high frequency. These apoptotic macrophages were colocalized in the end-plate regions. Apopto-sis is a major cause for elimination of infiltrating macrophages during the early phase of EAMG. © 1998 John Wiley & Sons, Inc. Muscle Nerve 21:1071–1074, 1998.