Stiffness of knee extensors in Duchenne Muscular Dystrophy

Authors

  • Christophe Cornu,

    1. Département de Génie Biologique, UMR—CNRS 6600, Université de Technologie de Compiègne, B.P. 20529, F-60205 Compiègne Cédex, France
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  • Francis Goubel PhD,

    Corresponding author
    1. Département de Génie Biologique, UMR—CNRS 6600, Université de Technologie de Compiègne, B.P. 20529, F-60205 Compiègne Cédex, France
    • Département de Génie Biologique, UMR—CNRS 6600, Université de Technologie de Compiègne, B.P. 20529, F-60205 Compiègne Cédex, France
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  • Michel Fardeau MD

    1. Unité INSERM 153, Institut de Myologie, Groupe Hospitalier Pitié-Salpétrière, Rue du Mur des Fermiers Généraux, 47 boulevard de l'Hôpital, 75013 Paris, France
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Abstract

The series elastic component (SEC) of Hill's muscle model is sensitive to a modification in muscle functional demand. In this study, SEC stiffness was quantified from quick-released movements in knee extensors of Duchenne muscular dystrophy (DMD) boys to look for possible modifications with the stage of disease. A SEC stiffness index (SI) was defined and was found significantly lower for controls than for DMD. Moreover, a linear relationship was established between mean SI and knee extensors involvement. This suggests a role for this parameter, together with other functional tests, for following patients with DMD. © 1998 John Wiley & Sons, Inc. Muscle Nerve 21: 1772–1774, 1998

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