MDI Special Article
Central mutation databases—A review
Article first published online: 27 DEC 1999
Copyright © 2000 Wiley-Liss, Inc.
Special Issue: The HUGO Mutation Database Initiative: Issues, Databases, and Perspectives for the New Millennium
Volume 15, Issue 1, pages 36–44, January 2000
How to Cite
Porter, C. J., Talbot, Jr., C. C. and Cuticchia, A. J. (2000), Central mutation databases—A review. Hum. Mutat., 15: 36–44. doi: 10.1002/(SICI)1098-1004(200001)15:1<36::AID-HUMU9>3.0.CO;2-D
- Issue published online: 27 DEC 1999
- Article first published online: 27 DEC 1999
- Manuscript Accepted: 11 OCT 1999
- Manuscript Received: 12 AUG 1999
- mutation database;
- central databases;
The Internet has been a key component in the coordination of the diverse group of scientists involved in the Human Genome Project. Nowhere has this contribution been more critical than in the maintenance and exchange of information about genetic variation and mutation. Whereas the majority of DNA sequence is generated and stored by a relatively few sites, a far greater number of researchers investigate the variations in that sequence from sites scattered worldwide. It falls to central databases to utilize the Internet to assemble data from these sites and make them available to the greater human genomic community. Hum Mutat 15:36–44, 2000. © 2000 Wiley-Liss, Inc.