Twin studies of eating disorders: A review
Version of Record online: 8 DEC 1999
Copyright © 2000 John Wiley & Sons, Inc.
International Journal of Eating Disorders
Volume 27, Issue 1, pages 1–20, January 2000
How to Cite
Bulik, C. M., Sullivan, P. F., Wade, T. D. and Kendler, K. S. (2000), Twin studies of eating disorders: A review. Int. J. Eat. Disord., 27: 1–20. doi: 10.1002/(SICI)1098-108X(200001)27:1<1::AID-EAT1>3.0.CO;2-Q
- Issue online: 8 DEC 1999
- Version of Record online: 8 DEC 1999
- Manuscript Accepted: 3 SEP 1999
- twin studies;
- genetic and environmental factors;
- eating disorders
Twin methodology has been used to delineate etiological factors in many medical disorders and behavioral traits including eating disorders. Although twin studies are powerful tools, their methodology can be arcane and their implications easily misinterpreted.
The goals of this study are to (a) review the theoretical rationale for twin studies; (b) provide a framework for their interpretation and evaluation; (c) review extant twin studies on eating disorders; and (d) explore the implications for understanding etiological issues in eating disorders.
On the basis of this review, it is not possible to draw firm conclusions regarding the precise contribution of genetic and environmental factors to anorexia nervosa. Twin studies confirm that bulimia nervosa is familial and reveal significant contributions of additive genetic effects and of unique environmental factors in liability to bulimia nervosa. The magnitude of the contribution of shared environment is less clear, but in the studies with the greatest statistical power, it appears to be less prominent than additive genetic factors. © 2000 by John Wiley & Sons, Inc. Int J Eat Disord 27: 1–20, 2000.