A method for three-dimensional time-resolved optical tomography
Article first published online: 11 MAY 2000
DOI: 10.1002/(SICI)1098-1098(2000)11:1<2::AID-IMA2>3.0.CO;2-J
Copyright © 2000 John Wiley & Sons, Inc.
Issue
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International Journal of Imaging Systems and Technology
Special Issue: Three-Dimensional Imaging
Volume 11, Issue 1, pages 2–11, 2000
Additional Information
How to Cite
Arridge, S. R., Hebden, J. C., Schweiger, M., Schmidt, F. E., Fry, M. E., Hillman, E. M., Dehghani, H. and Delpy, D. T. (2000), A method for three-dimensional time-resolved optical tomography. International Journal of Imaging Systems and Technology, 11: 2–11. doi: 10.1002/(SICI)1098-1098(2000)11:1<2::AID-IMA2>3.0.CO;2-J
Publication History
- Issue published online: 11 MAY 2000
- Article first published online: 11 MAY 2000
Funded by
- Wellcome Trust
- Abstract
- References
- Cited By
Abstract
We present an overview of time-resolved optical tomography together with the hardware and software methods that we have developed for a clinical instrument that implements this modality. The hardware is based on a multichannel photon-counting technique that records the histograms of photons time-of-flight through highly scattering and attenuating media. The software is based on a finite element model that is iteratively updated in order to minimize the difference between measured and modeled data. We have presented a first experimental reconstruction of a three-dimensional (3D) distribution of variable absorption and scattering coefficient, together with an ideal simulation of the same case. © 2000 John Wiley & Sons, Inc. Int J Imaging Syst Technol, 11, 2–11, 2000

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