Research Article

The use of electrophysiology for the assessment of diabetic neuropathy

  1. Joseph C. Arezzo*

Article first published online: 8 JAN 1999

DOI: 10.1002/(SICI)1520-6769(199707)21:1<13::AID-NRC203>3.0.CO;2-P

Issue

Neuroscience Research Communications

Neuroscience Research Communications

Special Issue: Proceedings of the Fourth International Symposium on Diabetic Neuropathy, and Neurodiab VII. July 15-19, 1997, Noordwijkerhout, The Netherlands

Volume 21, Issue 1, pages 13–23, July 1997

Additional Information

How to Cite

Arezzo, J. C. (1997), The use of electrophysiology for the assessment of diabetic neuropathy. Neuroscience Research Communications, 21: 13–23. doi: 10.1002/(SICI)1520-6769(199707)21:1<13::AID-NRC203>3.0.CO;2-P

Author Information

  1. Departments of Neuroscience and Neurology, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, New York 10461, USA

*Departments of Neuroscience and Neurology, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, New York 10461, USA

Publication History

  1. Issue published online: 8 JAN 1999
  2. Article first published online: 8 JAN 1999
  3. Manuscript Accepted: 9 MAY 1997

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Keywords:

  • diabetes mellitus;
  • electrophysiology;
  • nerve conduction;
  • neuropathy;
  • review

Abstract

Whole nerve electrophysiology can provide a battery of objective, reliable and specific measures that are sensitive to the progression of diabetic symmetrical polyneuropathy (DSPN). However, under standard conditions, these measures index limited aspects of neural activity, and then only in large diameter, myelinated axons. Nerve conduction is not synonymous with "nerve function." Electrophysiologic measures can be influenced by a variety of factors with different time courses of action and with different sensitivities to manipulation. The value of whole nerve electrophysiology must be based on a firm appreciation of the strengths and limitations of the procedure. © 1997 John Wiley & Sons, Ltd.

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