Eine konvergente Route zur Totalsynthese der Eleutheside

Authors

  • Xiao-Tao Chen,

    1. Department of Chemistry, Columbia University, Havemeyer Hall, New York, NY 10027, USA, Weitere Adresse:, Laboratory for Bioorganic Chemistry, Sloan-Kettering Institute for Cancer Research, 1275 York Avenue, New York, NY 10021, USA, Telefax: Int.+212/772-8691
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  • Clare E. Gutteridge,

    1. Department of Chemistry, Columbia University, Havemeyer Hall, New York, NY 10027, USA, Weitere Adresse:, Laboratory for Bioorganic Chemistry, Sloan-Kettering Institute for Cancer Research, 1275 York Avenue, New York, NY 10021, USA, Telefax: Int.+212/772-8691
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  • Samit K. Bhattacharya,

    1. Department of Chemistry, Columbia University, Havemeyer Hall, New York, NY 10027, USA, Weitere Adresse:, Laboratory for Bioorganic Chemistry, Sloan-Kettering Institute for Cancer Research, 1275 York Avenue, New York, NY 10021, USA, Telefax: Int.+212/772-8691
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  • Bishan Zhou,

    1. Department of Chemistry, Columbia University, Havemeyer Hall, New York, NY 10027, USA, Weitere Adresse:, Laboratory for Bioorganic Chemistry, Sloan-Kettering Institute for Cancer Research, 1275 York Avenue, New York, NY 10021, USA, Telefax: Int.+212/772-8691
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  • Thomas R. R. Pettus,

    1. Department of Chemistry, Columbia University, Havemeyer Hall, New York, NY 10027, USA, Weitere Adresse:, Laboratory for Bioorganic Chemistry, Sloan-Kettering Institute for Cancer Research, 1275 York Avenue, New York, NY 10021, USA, Telefax: Int.+212/772-8691
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  • Tony Hascall,

    1. Department of Chemistry, Columbia University, Havemeyer Hall, New York, NY 10027, USA, Weitere Adresse:, Laboratory for Bioorganic Chemistry, Sloan-Kettering Institute for Cancer Research, 1275 York Avenue, New York, NY 10021, USA, Telefax: Int.+212/772-8691
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  • Samuel J. Danishefsky

    1. Department of Chemistry, Columbia University, Havemeyer Hall, New York, NY 10027, USA, Weitere Adresse:, Laboratory for Bioorganic Chemistry, Sloan-Kettering Institute for Cancer Research, 1275 York Avenue, New York, NY 10021, USA, Telefax: Int.+212/772-8691
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Abstract

Eine Sequenz aus Ringerweiterung und Ringverengung ist einer der Schlüsselschritte bei der stereoselektiven Synthese des tricyclischen Eleuthesid-Grundgerüsts 2 ausgehend von α-Phellandren 1. Eleutheside sind Naturstoffe, die aus unterschiedlichen marinen Quellen isoliert wurden und von denen einige taxolähnliche Wirkung haben.

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