Phosphinic Acid Induced Reversal of Regioselectivity in Pd-Catalyzed Hydrophosphinylation of Alkynes with Ph2P(O)H

Authors


Abstract

One drop is enough to switch from hydropalladation to phosphinylpalladation. If one drop of diphenylphosphinic acid is added for the hydrophosphinylation of alkynes with diphenylphosphane oxide, there is a reversal in regioselectivity (as shown below).

Ancillary