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Chapter 11. Drug Treatment: Cholinesterase Inhibitors

  1. Alistair Burns3,
  2. Bengt Winblad4
  1. Michael Woodward1,
  2. Howard H. Feldman2

Published Online: 19 SEP 2006

DOI: 10.1002/0470010568.ch11

Severe Dementia

Severe Dementia

How to Cite

Woodward, M. and Feldman, H. H. (2006) Drug Treatment: Cholinesterase Inhibitors, in Severe Dementia (eds A. Burns and B. Winblad), John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/0470010568.ch11

Editor Information

  1. 3

    Department of Old Age Psychiatry, University of Manchester, Education and Research Centre, Wythenshawe Hospital, Manchester M23 9Lt, UK

  2. 4

    Division of Geriatric Medicine, Karolinska Institute, Neurotec B 84, Karolinska University Hospital, SE-14186 Stockholm, Sweden

Author Information

  1. 1

    Aged & Residential Care CSU Austin, Heidelberg Repatriation Hospital, PO Box 5444, Heidelberg West, Victoria, Australia

  2. 2

    Division of Neurology, University of British Columbia, 2329 West Mall, Vancouver V6T 1Z4, Canada

Publication History

  1. Published Online: 19 SEP 2006
  2. Published Print: 21 APR 2006

ISBN Information

Print ISBN: 9780470010549

Online ISBN: 9780470010563

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Keywords:

  • drug treatment - cholinesterase inhibitors;
  • therapy benefits measurement;
  • Goal Attainment Scaling;
  • add-on therapy;
  • Ginkgo biloba

Summary

This chapter contains sections titled:

  • Introduction

  • Acetylcholinesterase inhibitors in use

  • Measuring benefits of therapy

  • Efficacy of anticholinesterases in severe Alzheimer's disease

  • Add-on therapy

  • Head-to-head studies

  • Predictors of response

  • When and how should a cholinesterase inhibitor be trialled in severe dementia?

  • Future developments

  • References