Chapter 4. Pathogenesis of Obesity-Related Type 2 Diabetes

  1. Anthony H. Barnett Professor of Medicine and Consultant Physician2 and
  2. Sudhesh Kumar Professor of Medicine3
  1. Philip McTernan1 and
  2. Sudhesh Kumar Professor of Medicine3

Published Online: 7 FEB 2006

DOI: 10.1002/0470011106.ch4

Obesity and Diabetes

Obesity and Diabetes

How to Cite

McTernan, P. and Kumar, S. (2004) Pathogenesis of Obesity-Related Type 2 Diabetes, in Obesity and Diabetes (eds A. H. Barnett and S. Kumar), John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/0470011106.ch4

Editor Information

  1. 2

    Dept of Medicine/Diabetes/Endocrinology, Birmingham Heartlands Hospital, Birmingham, UK

  2. 3

    Diabetes & Metabolism, Warwick Medical School, University of Warwick, Coventry CV4 7AL, UK

Author Information

  1. 1

    Division of Clinical Sciences, Warwick Medical School, Coventry, UK

  2. 3

    Diabetes & Metabolism, Warwick Medical School, University of Warwick, Coventry CV4 7AL, UK

Publication History

  1. Published Online: 7 FEB 2006
  2. Published Print: 17 APR 2004

ISBN Information

Print ISBN: 9780470848982

Online ISBN: 9780470011102

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Summary

  • Introduction

  • Defining Fat Accumulation in Terms of Health Risk

  • Implications of Obesity-associated Diabetes

  • Development of Obesity-related Type 2 Diabetes

  • Fat Distribution

  • Evaluating Obesity-related Hypotheses for Progression of Type 2 Diabetes

  • Ectopic Fat Storage: Fat Content in Obesity

  • Lipid Metabolism in Adipose Tissue

  • Effects of NEFA on Hepatic Insulin Action

  • Adipose-tissue Derived Factors

  • Summary

  • References