Homeobox gene repertoires: implications for the evolution of diversity
Part 1. Genetics
1.1. Genetic Variation and Evolution
Published Online: 15 JAN 2005
Copyright © 2005 John Wiley & Sons, Ltd
Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics
How to Cite
Kappen, C. 2005. Homeobox gene repertoires: implications for the evolution of diversity. Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics. 1:1.1:3.
- Published Online: 15 JAN 2005
Homeobox genes are key regulators of morphogenetic processes in developing organisms, and are involved in the formation and differentiation of multiple tissues and cell types. The strong conservation of homeobox gene sequences indicates that many species share a common repertoire of homeobox genes. Experimental evidence provides support for conserved as well as divergent functions, raising the question how homeobox genes evolved in distinct species and in which way they contributed to the evolution of different morphologies. This article examines the composition of homeobox gene repertoires in diverse animals at the whole-genome level, with the aim to understand the underlying mechanisms of evolution in this multigene family.
- gene repertoire;
- molecular evolution;
- multigene family